NCOMMS−24−25010C Penetrating orocutaneous or oropharyngeal fistulas (POFs) are hard to treat, due to tissue deficiency, saliva contamination, and dynamic oral conditions. Here, the authors report a Janus hydrogel adhesive that prompts POF wound healing by seamless plugging of the penetrating wound, protecting it from mechanical stimuli and bacterial infection, and creating a pro-healing microenvironment.
- Ye Ju
- Chunyue Ma
- Qigang Wang