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Showing 1–50 of 74 results

Advanced filters: Author: Qingguo Li Clear advanced filters

Structural insights into the assembly and function of Retron Ec78 PtuAB

This study reports the cryo-EM structure of a Type I-A prokaryotic anti-phage defense mechanism, Retron Ec78, and in particular of the PtuA hexameric ATPase putatively bound to the PtuB nuclease. Beyond its known role in abortive infection via tRNA degradation, the authors demonstrate that the PtuAB complex also exhibits DNA-cleaving activity.

Leyuan Duan
Lu Chen
Qingguo Gong
ResearchOpen Access09 May 2026
Communications Biology

P: 1-10
Gradient Mn-La-Pt Catalysts with Three-layered Structure for Li-O₂ battery

Kedi Cai
Rui Yang
Tieshi He
ResearchOpen Access12 Oct 2016
Scientific Reports

Volume: 6, P: 1-8
Magnetic Resonance imaging (MRI) in detection of Bifidobacterium longum and Clostridium novyi-NT labeled with superparamagnetic iron oxide (SPIO) nanoparticle

Jianhua Wang
Xuebin Zhang
Dan Li
ResearchOpen Access22 Jul 2009
Nature Precedings

P: 1
Single-strand deaminase-assisted editing for functional RNA manipulation

A single-strand deaminase-assisted platform simultaneously rewrites multiple bases within a single RNA transcript.

Yuan Zhuang
Qingguo Zhu
Chengqi Yi
Research02 Jan 2026
Nature Biotechnology

P: 1-13
Nanometre-thin indium tin oxide for advanced high-performance electronics

Controlled physical vapour deposition of indium tin oxide layers with thickness down to 4 nm allows the use of these materials as active channels in high-performing transistors for digital and radiofrequency electronics.

Shengman Li
Mengchuan Tian
Yanqing Wu
Research12 Aug 2019
Nature Materials

Volume: 18, P: 1091-1097
Bright light exposure suppresses feeding and weight gain via a visual circuit linked to the lateral hypothalamus

Bright light reduces feeding and weight gain in mice by activating a specific retina-to-brain pathway that signals through the visual thalamus to inhibit appetite-regulating neurons in the hypothalamus.

Wen Li
Xiaodan Huang
Lu Huang
Research12 Dec 2025
Nature Neuroscience

Volume: 29, P: 632-646
Microbiome dysbiosis, neutrophil recruitment and mesenchymal transition of mesothelial cells promotes peritoneal metastasis of colorectal cancer

Li et al. show through single-cell and functional data that tumor microenvironment remodeling promotes peritoneal metastasis of colorectal cancer through microbiome dysbiosis, neutrophil recruitment and mesenchymal transition of mesothelial cells.

Qingguo Li
Yiwei Xiao
Guoxiang Cai
Research18 Feb 2025
Nature Cancer

Volume: 6, P: 493-510
Correction: Corrigendum: Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates

Pi-Xiao Wang
Yan-Xiao Ji
Hongliang Li
Amendments and Corrections01 Oct 2017
Nature Medicine

Volume: 23, P: 1241
Acidic pH environment induces autophagy in osteoblasts

Zhichao Zhang
Qingguo Lai
Yan Li
ResearchOpen Access06 Apr 2017
Scientific Reports

Volume: 7, P: 1-9
Endoscope-assisted resection of nonneoplastic space-occupying lesion in oral and maxillofacial areas

Yanan Li
Runqi Xue
Zhichao Zhang
ResearchOpen Access05 Dec 2017
Scientific Reports

Volume: 7, P: 1-7
A transcription factor ZmGLK36 confers broad resistance to maize rough dwarf disease in cereal crops

A novel resistance gene against maize rough dwarf disease was identified, which confers broad resistance to the virus pathogen infecting multiple cereal crops by regulating jasmonic acid (JA) biosynthesis and JA-mediated defence response.

Zhennan Xu
Zhiqiang Zhou
Xinhai Li
Research14 Sept 2023
Nature Plants

Volume: 9, P: 1720-1733
Spatial spillovers in producer services–manufacturing coordination: evidence from Chinese provinces

Xiaogang Zhou
Qingguo Xiong
Ling Huang
ResearchOpen Access27 Mar 2026
Scientific Reports

Volume: 16, P: 1-18
Chloroplast elongation factors break the growth–immunity trade-off by simultaneously promoting yield and defence

Enhanced expression of chloroplast elongation factors StTuA/B increases potato disease resistance and photosynthesis, while oomycete effector Pi22926 inhibits their entry into the chloroplasts by disrupting their phosphorylation by StMAP3Kβ2.

Yetong Qi
Jiahui Wu
Zhendong Tian
Research19 Sept 2024
Nature Plants

Volume: 10, P: 1576-1591
c-Rel is a myeloid checkpoint for cancer immunotherapy

Li et al. report that c-Rel, a member of the NF-κB transcription factor family, acts as a checkpoint for antitumor immunity as it promotes the generation of myeloid-derived suppressor cells and its inhibition in myeloid cells suppresses tumor growth.

Ting Li
Xinyuan Li
Youhai H. Chen
Research18 May 2020
Nature Cancer

Volume: 1, P: 507-517
Auricular malformations are driven by copy number variations in a hierarchical enhancer cluster and a dominant enhancer recapitulates human pathogenesis

Here, the authors identify a copy number variation containing three enhancers (PIHEC) that drives bilateral constricted ear by co-ordinately regulating HMX1 expression, revealing how aberrant Hmx1 expression in neural crest-derived fibroblasts disrupts outer ear development.

Xiaopeng Xu
Qi Chen
Yong-Biao Zhang
ResearchOpen Access17 May 2025
Nature Communications

Volume: 16, P: 1-23
Structural insights into dynamics of the BMV TLS aminoacylation

Brome Mosaic Virus utilises a tRNA-like structure (TLS) that interacts with tyrosyl-tRNA synthetase (TyrRS) during aminoacylation. Using cryo-EM, the authors captured multiple states of the TLS-TyrRS complex, revealing dynamic functional rearrangements.

Wen Yang
Ran Yi
Kaiming Zhang
ResearchOpen Access03 Feb 2025
Nature Communications

Volume: 16, P: 1-13
Methylammonium-free, high-efficiency, and stable all-perovskite tandem solar cells enabled by multifunctional rubidium acetate

The high trap density associated with tin (II) oxidation impacts the device performance of methylammonium cation-free tin-lead perovskite solar cells. Here, authors employ rubidium acetate for defect passivation and achieve efficient and stable single-junction and all-perovskite tandem solar cells.

Xufeng Liao
Xuefei Jia
Jinhui Tong
ResearchOpen Access30 Jan 2025
Nature Communications

Volume: 16, P: 1-9
Scalable high performance radio frequency electronics based on large domain bilayer MoS₂

Large area two-dimensional materials show promise for applications in DC and RF flexible electronics. Here, the authors report RF transistors based on chemical vapor deposited bilayer MoS₂ with 23 GHz extrinsic maximum oscillation frequency, and gigahertz mixers on flexible polyimide substrates.

Qingguo Gao
Zhenfeng Zhang
Yanqing Wu
ResearchOpen Access14 Nov 2018
Nature Communications

Volume: 9, P: 1-8
A modular three in one mucosal vaccine against three antigenic clusters of ACE2 using sarbecoviruses

Lin Liu
Haofeng Lin
Jingyi Yang
ResearchOpen Access20 Feb 2026
npj Vaccines

Volume: 11, P: 1-12
Remote on–off switching of protein activity by intrinsically disordered region

Here the authors uncover how a floppy tail in a protein acts as a remote switch, flipping activity on or off by tweaking internal motion, which reveals a powerful new way proteins regulate themselves without direct contact.

Tuo Ji
Piao Ge
Chengdong Huang
Research04 Jun 2025
Nature Structural & Molecular Biology

Volume: 32, P: 2088-2098
Nomograms for predicting the prognostic value of serological tumor biomarkers in colorectal cancer patients after radical resection

Qingguo Li
Weixing Dai
Sanjun Cai
ResearchOpen Access18 Apr 2017
Scientific Reports

Volume: 7, P: 1-10
Elucidating the Architectural dynamics of MuB filaments in bacteriophage Mu DNA transposition

Here, Zhao et al. use cryo-EM to show how MuB forms helical filaments around DNA. These structures play a crucial role in target DNA selection and transposition, shedding light on MuB’s functional mechanism.

Xiaolong Zhao
Yongxiang Gao
Shanshan Li
ResearchOpen Access31 Jul 2024
Nature Communications

Volume: 15, P: 1-14
Quasi-solid-state Zn-air batteries with an atomically dispersed cobalt electrocatalyst and organohydrogel electrolyte

Quasi-solid-state Zn-air batteries are limited by sluggish kinetics and low temperature incompatibility. Here, the authors use a single-atom catalyst and an organohydrogel electrolyte to enable a 100 mA cm⁻² cycling current density at 25 °C and a −60 to 60 °C operational window.

Qichen Wang
Qingguo Feng
Xiang Xiong
ResearchOpen Access27 Jun 2022
Nature Communications

Volume: 13, P: 1-10
Opposite monosynaptic scaling of BLP–vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory

How emotions affect memory is an open question. Here the authors establish learnt hopeful and learnt helpless mouse models, and find that posterior basolateral amygdala to ventral hippocampal CA1 monosynaptic glutamatergic inputs link emotions to spatial memory performance.

Ying Yang
Zhi-Hao Wang
Jian-Zhi Wang
ResearchOpen Access14 Jul 2016
Nature Communications

Volume: 7, P: 1-14
S-nitrosylation of phosphotransfer proteins represses cytokinin signaling

The interaction between nitric oxide and the plant phytohormone cytokinin has a critical role in regulating adaptation growth. Here Feng et al. find that nitric oxide-mediated S-nitrosylation of a phosphotransfer protein inhibits its phosphorylation, thereby repressing cytokinin signalling.

Jian Feng
Chun Wang
Jianru Zuo
Research26 Feb 2013
Nature Communications

Volume: 4, P: 1-9
Structural basis of the ligand binding and signaling mechanism of melatonin receptors

Melatonin receptors (MT1 and MT2) are the targets for melatonin, the major neurohormone involved in circadian rhythm and sleep regulation. Here the authors describe the structures of 2-iodomelatonin and ramelteon bound MT1–Gi and MT2-Gi, revealing that MT1 and MT2 possess distinctive features within the ligand-binding pocket.

Qinggong Wang
Qiuyuan Lu
Yuyong Tao
ResearchOpen Access24 Jan 2022
Nature Communications

Volume: 13, P: 1-10
Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer

Human telomeres are protected by a specialized shelterin complex composed of six proteins. Here the authors structurally characterize the interaction between the POT1-TPP1 shelterin component and identify mutations associated with genome instability and cancer that disrupt the POT1-TPP1 interaction.

Cong Chen
Peili Gu
Ming Lei
ResearchOpen Access10 Apr 2017
Nature Communications

Volume: 8, P: 1-15
Low-dose abiraterone plus Olaparib as a late-line treatment for mCRPC patients without BRCA1/2 mutations: a multicenter retrospective pilot study

Sijin Chen
Dewen Zhong
Jinfeng Wu
ResearchOpen Access27 Aug 2024
Scientific Reports

Volume: 14, P: 1-6
Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation

Mouse incisor growth depends upon mesenchymal stromal cells (MSCs) and transit amplifying cells (TACs). Here the authors describe a distinct population of MSCs that is maintained by TACs through Dlk1 ligand and that contribute to MTACs and mesenchymal lineages including dental pulp and odontoblasts.

Jemma Victoria Walker
Heng Zhuang
Bing Hu
ResearchOpen Access09 Aug 2019
Nature Communications

Volume: 10, P: 1-18
Effect of Lymph Node Count on Pathological Stage III Rectal Cancer with Preoperative Radiotherapy

Qingguo Li
Lei Liang
Sanjun Cai
ResearchOpen Access19 Nov 2015
Scientific Reports

Volume: 5, P: 1-9
miR-139-5p Inhibits the Epithelial-Mesenchymal Transition and Enhances the Chemotherapeutic Sensitivity of Colorectal Cancer Cells by Downregulating BCL2

Qingguo Li
Xin Liang
Guoxiang Cai
ResearchOpen Access31 May 2016
Scientific Reports

Volume: 6, P: 1-10
FOXI3 pathogenic variants cause one form of craniofacial microsomia

Most cases of craniofacial microsomia are sporadic but familial cases have been reported. Here the authors report that variants in FOXI3 can cause a small fraction of cases with different modes of inheritance including autosomal dominant with reduced penetrance.

Ke Mao
Christelle Borel
Stylianos E. Antonarakis
ResearchOpen Access11 Apr 2023
Nature Communications

Volume: 14, P: 1-16
Two-sample mendelian randomization reveals a causal association between membranous nephropathy and lung cancer

A two-sample Mendelian randomization study identifies a causal effect of membranous nephropathy on lung cancer, suggesting that membranous nephropathy may be an exposure factor for lung cancer.

Kezhen Yang
Xiaofeng Ding
Pingna Zhang
ResearchOpen Access01 Sept 2023
Communications Biology

Volume: 6, P: 1-7
Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates

Targeting CFLAR in mouse and non-human primates ameliorates non-alcoholic steatohepatitis by decreasing JNK signaling in hepatocytes.

Pi-Xiao Wang
Yan-Xiao Ji
Hongliang Li
Research20 Feb 2017
Nature Medicine

Volume: 23, P: 439-449
Wang et al. reply

Pi-Xiao Wang
Guang-Nian Zhao
Hongliang Li
Correspondence04 Jun 2018
Nature Medicine

Volume: 24, P: 700-701
Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4

Toll-like receptor (TLR) 4 is a key mediator of non-alcoholic fatty liver disease progression. Targeting TLR4 degradation via the lysosome pathway improves outcome in mouse and monkey models of this condition.

Guang-Nian Zhao
Peng Zhang
Hongliang Li
Research08 May 2017
Nature Medicine

Volume: 23, P: 742-752
Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia

Craniofacial microsomia is a congenital anomaly that affects the development of the skull. Here, the authors perform a genome-wide association study on patients in China and identify particular loci that provide insights into genetic mechanisms.

Yong-Biao Zhang
Jintian Hu
Qingguo Zhang
ResearchOpen Access08 Feb 2016
Nature Communications

Volume: 7, P: 1-9
MicroRNA-122 ameliorates corneal allograft rejection through the downregulation of its target CPEB1

Ting Wang
Fengjie Li
Weiyun Shi
ResearchOpen Access15 May 2017
Cell Death Discovery

Volume: 3, P: 1-7
Adsorption of methylene blue on an agro-waste oiltea shell with and without fungal treatment

Jiayang Liu
Enzhong Li
Qingguo Huang
ResearchOpen Access05 Dec 2016
Scientific Reports

Volume: 6, P: 1-10
The FOXC1/FBP1 signaling axis promotes colorectal cancer proliferation by enhancing the Warburg effect

Qingguo Li
Ping Wei
Dawei Li
Research31 Aug 2018
Oncogene

Volume: 38, P: 483-496
The effect of anionic emulsifiers’ diversity and manufacturing processes on the stability and mechanical properties of the water-based epoxy-emulsified asphalt

Yi Peng
Jinke Miao
Tao Ao
ResearchOpen Access27 Sept 2024
Scientific Reports

Volume: 14, P: 1-22
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions

Zhou Yu
Jing Ma
Zhe Wang
ResearchOpen Access02 Jul 2018
Scientific Reports

Volume: 8, P: 1-12
Primary Astrocytic Tumours and Paired Recurrences have Similar Biological Features in IDH1, TP53 and TERTp Mutation and MGMT, ATRX Loss

Xia Li
Jie Wei
Zhe Wang
ResearchOpen Access12 Oct 2017
Scientific Reports

Volume: 7, P: 1-10
Predicting Parkinson’s disease and its progression based on radiomics in T1-weight images and α‑synuclein in cerebrospinal fluid

Xu Zhang
Hui Li
Qingguo Ren
ResearchOpen Access25 Sept 2025
npj Parkinson's Disease

Volume: 11, P: 1-12
Enhancing hepatoprotective action: oxyberberine amorphous solid dispersion system targeting TLR4

Tingting Chen
Qingguo Li
Yaoxing Dou
ResearchOpen Access28 Jun 2024
Scientific Reports

Volume: 14, P: 1-18
Enhancing the performance of SSVEP-based BCIs by combining task-related component analysis and deep neural network

Qingguo Wei
Chang Li
Xiaorong Gao
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-16
Nasal vaccination of triple-RBD scaffold protein with flagellin elicits long-term protection against SARS-CoV-2 variants including JN.1

Xian Li
Mengxin Xu
Yao-Qing Chen
ResearchOpen Access27 Apr 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-12
GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy stress and augments the efficacy of current colorectal cancer therapies

Weixing Dai
Ye Xu
Guoxiang Cai
ResearchOpen Access02 Sept 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-14
5-hydroxymethylcytosine loss is associated with poor prognosis for patients with WHO grade II diffuse astrocytomas

Feng Zhang
Yifan Liu
Qing Li
ResearchOpen Access11 Feb 2016
Scientific Reports

Volume: 6, P: 1-14
Erratum: Adsorption of methylene blue on an agro-waste oiltea shell with and without fungal treatment

Jiayang Liu
Enzhong Li
Qingguo Huang
Amendments and CorrectionsOpen Access16 Mar 2017
Scientific Reports

Volume: 7, P: 1

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