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Hepatic HMGCS2-derived β-hydroxybutyrate attenuates hippocampal insulin resistance and neuroinflammation to promote MASLD-induced cognitive function

Fatty liver disease may harm the brain by starving it of a protective fuel. This study shows that restoring this fuel, BHB, can rescue memory and brain health, revealing a direct liver-brain link and a promising treatment target.

Lijuan Nie
Jing Sun
Xiqiao Zhou
ResearchOpen Access10 Jan 2026
Communications Biology

P: 1-13
A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients

Alternative polyadenylation (APA) regulates the length of the 3′UTR of mRNA. Here, the authors describe a method to accurately measure APA in tumours and apply this method to investigate the differences in APA in African American and European American lung cancer samples.

Adriana Zingone
Sanju Sinha
Bríd M. Ryan
ResearchOpen Access23 Sept 2021
Nature Communications

Volume: 12, P: 1-12
Ambient temperature and emergency department visits for mental disorder before and during the COVID-19 pandemic

Authors analyze the associations of emergency admissions related to mental health disorders with short-term temperature changes before and during the COVID-19 pandemic, providing evidence for increased risks for depression-related visits associated with elevated temperatures during the pandemic.

Keyu Wu
Junwei Yan
Jian Cheng
Research05 Feb 2024
Nature Mental Health

Volume: 2, P: 278-286
Decreased bilateral thalamic gray matter volume in first-episode schizophrenia with prominent hallucinatory symptoms: A volumetric MRI study

Peng Huang
Yibin Xi
Hong Yin
ResearchOpen Access25 Sept 2015
Scientific Reports

Volume: 5, P: 1-10
The effects of manganese oxide octahedral molecular sieve chitosan microspheres on sludge bacterial community structures during sewage biological treatment

Fei Pan
Wen Liu
Dongsheng Xia
ResearchOpen Access21 Nov 2016
Scientific Reports

Volume: 6, P: 1-11
Cannabinoid receptor subtype 2 (CB₂R) agonist, GW405833 reduces agonist-induced Ca²⁺ oscillations in mouse pancreatic acinar cells

Zebing Huang
Haiyan Wang
Jie Wu
ResearchOpen Access19 Jul 2016
Scientific Reports

Volume: 6, P: 1-14

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Hepatic HMGCS2-derived β-hydroxybutyrate attenuates hippocampal insulin resistance and neuroinflammation to promote MASLD-induced cognitive function

A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients

Ambient temperature and emergency department visits for mental disorder before and during the COVID-19 pandemic

Decreased bilateral thalamic gray matter volume in first-episode schizophrenia with prominent hallucinatory symptoms: A volumetric MRI study

The effects of manganese oxide octahedral molecular sieve chitosan microspheres on sludge bacterial community structures during sewage biological treatment

Cannabinoid receptor subtype 2 (CB2R) agonist, GW405833 reduces agonist-induced Ca2+ oscillations in mouse pancreatic acinar cells

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Cannabinoid receptor subtype 2 (CB₂R) agonist, GW405833 reduces agonist-induced Ca²⁺ oscillations in mouse pancreatic acinar cells