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Advanced filters: Author: Qiying Fan Clear advanced filters

Multimodal learning with next-token prediction for large multimodal models

Emu3 enables large-scale text, image and video learning based solely on next-token prediction, matching the generation and perception performance of task-specific methods, with implications for the development of scalable and unified multimodal intelligence systems.

Xinlong Wang
Yufeng Cui
Tiejun Huang
ResearchOpen Access28 Jan 2026
Nature

P: 1-7
Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin

The vascular endothelium contributes to metabolic regulation, however, the underlying mechanisms are not fully understood. Here the authors show that endothelial low-density lipoprotein receptor-related protein 1 regulates glucose homeostasis via osteocalcin expression.

Hua Mao
Luge Li
Xinchun Pi
ResearchOpen Access06 Sept 2021
Nature Communications

Volume: 12, P: 1-12
Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance

Type 2 diabetes is associated with chronic inflammation and is characterized by insulin resistance. Here, the authors identify a crucial role for endothelial BMPER function in glucose homeostasis, and BMPER overexpression was shown to alleviate insulin resistance and hyperglycemia in diabetic mice.

Hua Mao
Luge Li
Xinchun Pi
ResearchOpen Access26 Mar 2021
Nature Communications

Volume: 12, P: 1-10