B cell receptors (BCR) are the membrane-bound counterparts of antibodies, and the role of N-linked glycans in their functions are much less known than that of circulating immunoglobulins. Here authors study the site-specific glycosylation profiles of all 4 N-linked glycosylation sites of human Igµ BCRs expressed in naïve and memory B cells and conclude that these show high level of conservation across development and don’t contribute to differences in their expression and function.
- M. D. Holborough-Kerkvliet
- L. Hafkenscheid
- R. E. M. Toes
