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Showing 1–50 of 62 results

Advanced filters: Author: RICHARD A. BLOOMFIELD Clear advanced filters

Nature of the Photoreactivable Ultra-Violet Lesion in Deoxyribonucleic Acid

JANE K. SETLOW
RICHARD B. SETLOW
Research09 Feb 1963
Nature

Volume: 197, P: 560-562
Phenylalanine Metabolism altered by Dietary Dieldrin

PAUL M. MEHRLE
MARY E. DECLUE
RICHARD A. BLOOMFIELD
Research25 Aug 1972
Nature

Volume: 238, P: 462-463
Multiomic profiling identifies predictors of survival in African American patients with acute myeloid leukemia

Analysis of exomes and transcriptomes from 100 African American patients with acute myeloid leukemia identifies ancestry-related variation in mutation profiles and survival. Refined risk classification suggests clinical relevance of these ancestry-associated differences.

Andrew Stiff
Maarten Fornerod
Ann-Kathrin Eisfeld
ResearchOpen Access04 Oct 2024
Nature Genetics

Volume: 56, P: 2434-2446
A Potent New Benzothiadiazine Diuretic

RICHARD M. TAYLOR
MARTIN M. WINBURY
Research13 Aug 1960
Nature

Volume: 187, P: 603-604
Dual Neurosecretory Innervation of the Adenohypophysis of Hippocampus, the Sea-horse

FRANCIS KNOWLES
LUTZ VOLLRATH
RICHARD S. NISHIOKA
Research15 Apr 1967
Nature

Volume: 214, P: 309
Comparison of four independently determined structures of human recombinant interleukin–4

Lorna J. Smith
Christina Redfield
Alexander Wlodawer
Research01 May 1994
Nature Structural Biology

Volume: 1, P: 301-310
Can microvolt T-wave alternans testing reduce unnecessary defibrillator implantation?

As defibrillator therapy is invasive and expensive, using a defibrillator as primary prevention therapy requires risk stratification to identify suitable patients at significant risk. In this review Antonis A Armoundaset alevaluate whether clinical data support the use of microvolt T-wave alternans testing to identify patients who are unlikely to benefit from primary prevention implantable cardioverter-defibrillator therapy.

Antonis A Armoundas
Stefan H Hohnloser
Richard J Cohen
Reviews01 Oct 2005
Nature Clinical Practice Cardiovascular Medicine

Volume: 2, P: 522-528
Three-dimensional NMR spectroscopy of a protein in solution

Hartmut Oschkinat
Christian Griesinger
G. Marius Clore
Research24 Mar 1988
Nature

Volume: 332, P: 374-376
Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptamine

A. Richard Green
David G. Grahame-Smith
Research08 Apr 1976
Nature

Volume: 260, P: 487-491
Ozone depletion in the upper stratosphere estimated from satellite and Space Shuttle data

Ernest Hilsenrath
Richard P. Cebula
Charles H. Jackman
Research09 Jul 1992
Nature

Volume: 358, P: 131-133
Dose-response relationships for resetting of human circadian clock by light

Diane B. Boivin
Jeanne F. Duffy
Charles A. Czeisler
Research08 Feb 1996
Nature

Volume: 379, P: 540-542
Impact of Chronic Protein-Calorie Malnutrition on Small Intestinal Repair after Acute Viral Enteritis: A Study in Gnotobiotic Piglets

J Decker Butzner
Daniel G Butler
J Richard Hamilton
Research01 May 1985
Pediatric Research

Volume: 19, P: 476-481
Unsettling antibiosis: how might interdisciplinary researchers generate a feeling for the microbiome and to what effect?

Beth Greenhough
Andrew Dwyer
Jamie Lorimer
ResearchOpen Access11 Dec 2018
Palgrave Communications

Volume: 4, P: 1-12
Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia

Acute lymphoblastic leukaemia is characterized by chromosomal rearrangements. Here, the authors carry out RNA-sequencing on a large cohort of patients and identify recurrent rearrangements of MEF2D, which lead to increased transcriptional activity of the gene, and cellular transformation in vitro.

Zhaohui Gu
Michelle Churchman
Charles G. Mullighan
ResearchOpen Access08 Nov 2016
Nature Communications

Volume: 7, P: 1-10
Convergence in phosphorus constraints to photosynthesis in forests around the world

Phosphorus (P) limitation is pervasive in tropical forests. Here the authors analyse the dependence of photosynthesis on leaf N and P in tropical forests, and show that incorporating leaf P constraints in a terrestrial biosphere model enhances its predictive power.

David S. Ellsworth
Kristine Y. Crous
Ian J. Wright
ResearchOpen Access25 Aug 2022
Nature Communications

Volume: 13, P: 1-12
Chromosome 5q deletion and epigenetic suppression of the gene encoding α-catenin (CTNNA1) in myeloid cell transformation

Ting Xi Liu
Michael W Becker
A Thomas Look
Research10 Dec 2006
Nature Medicine

Volume: 13, P: 78-83
Automatic emotion and attention analysis of young children at home: a ResearchKit autism feasibility study

Helen L. Egger
Geraldine Dawson
Guillermo Sapiro
ResearchOpen Access01 Jun 2018
npj Digital Medicine

Volume: 1, P: 1-10
Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Protein arginine methyltransferases (PRMTs) are increasingly recognized as potential therapeutic targets but PRMT7 remains an understudied member of this enzyme family. Here, the authors develop a chemical probe for PRMT7 and apply it to elucidate the role of PRMT7 in the cellular stress response.

Magdalena M. Szewczyk
Yoshinori Ishikawa
Dalia Barsyte-Lovejoy
ResearchOpen Access14 May 2020
Nature Communications

Volume: 11, P: 1-15
Deregulation of DUX4 and ERG in acute lymphoblastic leukemia

Charles Mullighan, Jinghui Zhang and colleagues characterize a subtype of B-progenitor acute lymphoblastic leukemia with deregulated DUX4 and ERG. They find that aberrant DUX4 activation results in loss of ERG function, either through deletion or by the induction a novel transforming ERG isoform, ERGalt, that inhibits wild-type ERG activity.

Jinghui Zhang
Kelly McCastlain
Charles G Mullighan
Research24 Oct 2016
Nature Genetics

Volume: 48, P: 1481-1489
Multi-dimensional analysis of adult acute myeloid leukemia cross-continents reveals age-associated trends in mutational landscape and treatment outcomes (Acute Myeloid Leukemia Cooperative Group & Alliance for Clinical Trials in Oncology)

Monica Cusan
Karilyn Larkin
Ann-Kathrin Eisfeld
ResearchOpen Access19 Sept 2025
Leukemia

Volume: 39, P: 2926-2934
Phenology and related traits for wheat adaptation

Jessica Hyles
Maxwell T. Bloomfield
Ben Trevaskis
ReviewsOpen Access26 May 2020
Heredity

Volume: 125, P: 417-430
Flagella-like beating of actin bundles driven by self-organized myosin waves

Cilia are composed of cytoskeletal filaments and molecular motors and are characterized by a wave-like motion. Here the authors show that this motion is reconstituted in vitro from the self-assembly of polymerizing actin filaments and myosin motors.

Marie Pochitaloff
Martin Miranda
Pascal Martin
Research08 Aug 2022
Nature Physics

Volume: 18, P: 1240-1247
Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery

Mice engineered to express the entire human variable immunoglobulin region enable rapid isolation of high-affinity antibodies specific for antigens of interest.

E-Chiang Lee
Qi Liang
Allan Bradley
Research16 Mar 2014
Nature Biotechnology

Volume: 32, P: 356-363
Target RNA motif and target mRNAs of the Quaking STAR protein

André Galarneau
Stéphane Richard
Research24 Jul 2005
Nature Structural & Molecular Biology

Volume: 12, P: 691-698
An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia

Lasry and Nadorp et al. use single-cell RNA sequencing and CITE sequencing to reveal inflammatory gene expression in a subset of pediatric and adult patients with acute myeloid leukemia that associates with changes in the immune microenvironment and generate an inflammatory score with prognostic potential.

Audrey Lasry
Bettina Nadorp
Iannis Aifantis
Research29 Dec 2022
Nature Cancer

Volume: 4, P: 27-42
Protection of p27^Kip1 mRNA by quaking RNA binding proteins promotes oligodendrocyte differentiation

Daniel Larocque
André Galarneau
Stéphane Richard
Research28 Nov 2004
Nature Neuroscience

Volume: 8, P: 27-33
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

Timothy J. Ley
Elaine R. Mardis
Richard K. Wilson
ResearchOpen Access06 Nov 2008
Nature

Volume: 456, P: 66-72
Sam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasis

S Richard
G Vogel
K E Lukong
Research09 Jul 2007
Oncogene

Volume: 27, P: 548-556
Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells

The NF-κB complex is a core regulator of inflammatory gene expression and activates transcription of many different target genes. Fu et al. show that NF-κB promoter specificity can be tuned by Sam68, which is required for targeting NF-κB to the CD25 promoter during T cell activation.

Kai Fu
Xin Sun
Fengyi Wan
Research28 May 2013
Nature Communications

Volume: 4, P: 1-11
Engineering receptor-mediated cytotoxicity into human ribonucleases by steric blockade of inhibitor interaction

Motoshi Suzuki
Shailendra K. Saxena
Richard J. Youle
Research01 Mar 1999
Nature Biotechnology

Volume: 17, P: 265-270
Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs

Surbhi Dhar
Vidyasiri Vemulapalli
Mark T. Bedford
ResearchOpen Access19 Feb 2013
Scientific Reports

Volume: 3, P: 1-6
Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial

Richard A. Larson
Sumithra J. Mandrekar
Richard M. Stone
Research02 Mar 2021
Leukemia

Volume: 35, P: 2539-2551
Author Correction: An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia

Audrey Lasry
Bettina Nadorp
Iannis Aifantis
Amendments and Corrections19 Jan 2023
Nature Cancer

Volume: 4, P: 149
“Quality of life”: parent and neonatologist perspectives

Shannon Y. Adams
Richard Tucker
Beatrice E. Lechner
Research25 Mar 2020
Journal of Perinatology

Volume: 40, P: 1809-1820
Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results

Frank G. Rücker
Ling Du
Konstanze Döhner
ResearchOpen Access28 Jul 2021
Leukemia

Volume: 36, P: 90-99
Arginine methylation signals mRNA export

The implication of arginine methylation in mRNA biogenesis from transcription to mRNA export has been documented by various groups, but the precise role of methylation in this process is still unknown. A recent study demonstrates that in Saccharomyces cerevisiae methylation modulates the interaction and recruitment of components of the RNA packaging and export machinery.

Kiven E Lukong
Stéphane Richard
News & Views01 Oct 2004
Nature Structural & Molecular Biology

Volume: 11, P: 914-915
Are Twins Growth Restricted?

Beverly S Muhlhausler
Serina N Hancock
Richard Harding
Reviews01 Aug 2011
Pediatric Research

Volume: 70, P: 117-122
Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Magdalena M. Szewczyk
Yoshinori Ishikawa
Dalia Barsyte-Lovejoy
Amendments and CorrectionsOpen Access26 May 2020
Nature Communications

Volume: 11, P: 1
PAR1 activation induces rapid changes in glutamate uptake and astrocyte morphology

Amanda M. Sweeney
Kelsey E. Fleming
Annalisa Scimemi
ResearchOpen Access03 Mar 2017
Scientific Reports

Volume: 7, P: 1-20
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

Edward J Saunders
Tokhir Dadaev
Zsofia Kote-Jarai
ResearchOpen Access10 Mar 2016
British Journal of Cancer

Volume: 114, P: 945-952
Genome-wide association study identifies an acute myeloid leukemia susceptibility locus near BICRA

Christopher J. Walker
Christopher C. Oakes
Clara D. Bloomfield
Research05 Oct 2018
Leukemia

Volume: 33, P: 771-775
Loss of p53 in quaking viable mice leads to Purkinje cell defects and reduced survival

Christina Gavino
Stéphane Richard
ResearchOpen Access06 Sept 2011
Scientific Reports

Volume: 1, P: 1-6
Comparison of clinical and molecular characteristics of patients with acute myeloid leukemia and either TP73 or TP53 mutations

Alice S. Mims
Jessica Kohlschmidt
Clara D. Bloomfield
Research05 Aug 2020
Leukemia

Volume: 35, P: 1188-1192
Arginine methylation of hnRNPUL1 regulates interaction with NBS1 and recruitment to sites of DNA damage

Gayathri Gurunathan
Zhenbao Yu
Stéphane Richard
ResearchOpen Access28 May 2015
Scientific Reports

Volume: 5, P: 1-9
Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial

Nikolaus Jahn
Ekaterina Jahn
Konstanze Döhner
ResearchOpen Access03 Aug 2022
Leukemia

Volume: 36, P: 2218-2227
Complex karyotype in de novo acute myeloid leukemia: typical and atypical subtypes differ molecularly and clinically

Krzysztof Mrózek
Ann-Kathrin Eisfeld
Clara D. Bloomfield
Research08 Feb 2019
Leukemia

Volume: 33, P: 1620-1634
NF1 mutations are recurrent in adult acute myeloid leukemia and confer poor outcome

Ann-Kathrin Eisfeld
Jessica Kohlschmidt
Clara D. Bloomfield
Research05 Jun 2018
Leukemia

Volume: 32, P: 2536-2545
Allogeneic hematopoietic cell transplantation compared to chemotherapy consolidation in older acute myeloid leukemia (AML) patients 60–75 years in first complete remission (CR1): an alliance (A151509), SWOG, ECOG-ACRIN, and CIBMTR study

Celalettin Ustun
Jennifer Le-Rademacher
Andrew S. Artz
Research09 May 2019
Leukemia

Volume: 33, P: 2599-2609
The melanoma-specific graded prognostic assessment does not adequately discriminate prognosis in a modern population with brain metastases from malignant melanoma

Anna Wilkins
Andrew Furness
Kevin Harrington
ResearchOpen Access20 Oct 2015
British Journal of Cancer

Volume: 113, P: 1275-1281
Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies

Ann-Kathrin Eisfeld
Jessica Kohlschmidt
Clara D. Bloomfield
Research25 Feb 2018
Leukemia

Volume: 32, P: 1338-1348

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