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Showing 1–9 of 9 results
Advanced filters: Author: Raphael Sieber Clear advanced filters

  • Roer et al. analyze genomes of Escherichia coli clonal complex 38 from humans, animals, and food to investigate its spread and host associations. They find distinct human and poultry lineages and identify plasmid markers linked to animal adaptation and zoonotic transmission.

    • Louise Roer
    • Astrid Rasmussen
    • Marc Stegger
    ResearchOpen Access
    Communications Medicine
    P: 1-12

  • In this study, the authors compare the transmission dynamics of the Delta and Omicron SARS-CoV-2 variants using household data from Denmark. They find that Omicron has a higher secondary attack rate, and that the odds of infection with Omicron was higher than with Delta, particularly for vaccinated individuals.

    • Frederik Plesner Lyngse
    • Laust Hvas Mortensen
    • Carsten Thure Kirkeby
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-7

  • In this study, the authors use household data from Denmark to investigate the transmissibility of the BA.1 and BA.2 Omicron SARS-CoV-2 subvariants. They find that the secondary attack rate was higher for BA.2, but that it had higher infectiousness only when cases were not vaccinated.

    • Frederik Plesner Lyngse
    • Carsten Thure Kirkeby
    • Laust Hvas Mortensen
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-7

  • COVID-19 vaccines may reduce the susceptibility of an individual to infection and/or the infectiousness of breakthrough infections. Here, the authors use data from Denmark and estimate that vaccine effectiveness was 61% for susceptibility and 31% for infectiousness during a period of Delta variant dominance.

    • Frederik Plesner Lyngse
    • Kåre Mølbak
    • Carsten Thure Kirkeby
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-8

  • Methicillin-resistant strains of Staphylococcus aureus appeared in European hedgehogs in the pre-antibiotic era as a co-evolutionary adaptation to antibiotic-producing dermatophytes and have spread within the local hedgehog populations and between hedgehogs and secondary hosts.

    • Jesper Larsen
    • Claire L. Raisen
    • Anders R. Larsen
    ResearchOpen Access
    Nature
    Volume: 602, P: 135-141

  • KRASG12V and BRAFV600E are oncogenic mutations that activate ERK signalling. Here, the authors use single cell analysis in intestinal organoids and show that BRAFV600E activates ERK in all intestinal cell types, while KRASG12V induces ERK activation in only a subset of cells, depending on cell differentiation state.

    • Raphael Brandt
    • Thomas Sell
    • Markus Morkel
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-15

  • A high proportion of confirmed SARS-CoV-2 cases in Denmark were sequenced during the pandemic and linked to demographic, spatial and temporal data. Here, the authors analyse 290,000 genomes sampled in 2021 to demonstrate the value of this high coverage, detailed data set.

    • Mark P. Khurana
    • Jacob Curran-Sebastian
    • Samir Bhatt
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • Establishing the relative transmissibility of emerging variants of SARS-CoV-2 is key for pandemic management. Here, the authors use full-population administrative data from Denmark linked to PCR test results and estimate that the Alpha variant was ~60% higher than other strains circulating in early 2021.

    • Frederik Plesner Lyngse
    • Kåre Mølbak
    • Carsten Thure Kirkeby
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-8