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Crystal structure at 1.7 Å of the bovine papillomavirus-1 E2 DMA-binding domain bound to its DNA target

Rashmi S. Hegde
Steven R. Grossman
Paul B. Sigler
Research08 Oct 1992
Nature

Volume: 359, P: 505-512
The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension

Survival and proliferation of vascular cells in the presence of DNA damage is a characteristic of pulmonary arterial hypertension. Here the authors show that the phosphatase EYA3 contributes to vascular remodeling by promoting survival of damaged cells, and present results of genetic and pharmacological EYA3 inhibition.

Yuhua Wang
Ram Naresh Pandey
Rashmi S. Hegde
ResearchOpen Access12 Sept 2019
Nature Communications

Volume: 10, P: 1-13
BIK, the founding member of the BH3-only family proteins: mechanisms of cell death and role in cancer and pathogenic processes

G Chinnadurai
S Vijayalingam
R Rashmi
Reviews30 Jul 2009
Oncogene

Volume: 27, P: S20-S29
Author Correction: Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48

Saima Riazuddin
Inna A. Belyantseva
Zubair M. Ahmed
Amendments and Corrections26 Aug 2025
Nature Genetics

Volume: 57, P: 2340-2342
A direct and melanopsin-dependent fetal light response regulates mouse eye development

During retinal vascular development there is simultaneous regression of the hyaloid vasculature and formation of the retinal vasculature; here it is demonstrated that regression of developing vasculature is light dependent and acts via the photoreceptor melanopsin.

Sujata Rao
Christina Chun
Richard A. Lang
Research16 Jan 2013
Nature

Volume: 494, P: 243-246
Eyes absent represents a class of protein tyrosine phosphatases

Jayanagendra P. Rayapureddi
Chandramohan Kattamuri
Rashmi S. Hegde
Research20 Nov 2003
Nature

Volume: 426, P: 295-298
Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

The common dust mite allergen Der p 2 is shown to replace MD-2 as the lipopolysaccharide-binding component and facilitates signalling through TLR4. It is suggested that Der p 2 tends to be targeted by adaptive immune responses because of its auto-adjuvant properties.

Aurelien Trompette
Senad Divanovic
Christopher L. Karp
Research07 Dec 2008
Nature

Volume: 457, P: 585-588
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

The Eyes Absent proteins (EYA1-4) are a group of tyrosine phosphatases. Here, the authors report a signalling pathway in which EYA4 and EYA1 dephosphorylate Polo-like kinase 1 (PLK1) at pY445 to support PLK1 activation and mitosis.

Christopher B. Nelson
Samuel Rogers
Hilda A. Pickett
ResearchOpen Access15 Feb 2024
Nature Communications

Volume: 15, P: 1-17
An opsin 5–dopamine pathway mediates light-dependent vascular development in the eye

Nguyen et al. show that neuropsin (OPN5) suppresses hyaloid vessel regression in the developing mouse retina in response to light, by regulation of the dopamine reuptake transporter and DRD2-dependent suppression of VEGFR2 activity.

Minh-Thanh T. Nguyen
Shruti Vemaraju
Richard A. Lang
Research01 Apr 2019
Nature Cell Biology

Volume: 21, P: 420-429
The crystal structure of the bacterial chaperonln GroEL at 2.8 Å

Kerstin Braig
Zbyszek Otwinowski
Paul B. Sigler
Research13 Oct 1994
Nature

Volume: 371, P: 578-586
The Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cells

R N Pandey
R Rani
R S Hegde
Research26 Apr 2010
Oncogene

Volume: 29, P: 3715-3722
Advancing educational data mining for enhanced student performance prediction: a fusion of feature selection algorithms and classification techniques with dynamic feature ensemble evolution

Saleem Malik
S. Gopal Krishna Patro
Naoufel Kraiem
ResearchOpen Access13 Mar 2025
Scientific Reports

Volume: 15, P: 1-28
Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48

Zubair Ahmed and colleagues identify homozygous mutations in CIB2, a gene that encodes a calcium- and integrin-binding protein, that cause Usher syndrome type 1J and nonsyndromic deafness DFNB48. CIB2 is required for hair cell development and retinal photoreceptor cells in zebrafish and Drosophila melanogaster.

Saima Riazuddin
Inna A Belyantseva
Zubair M Ahmed
Research30 Sept 2012
Nature Genetics

Volume: 44, P: 1265-1271
Novel and recurrent CIB2 variants, associated with nonsyndromic deafness, do not affect calcium buffering and localization in hair cells

Celia Zazo Seco
Arnaud P Giese
Hannie Kremer
Research15 Jul 2015
European Journal of Human Genetics

Volume: 24, P: 542-549

Search

Crystal structure at 1.7 Å of the bovine papillomavirus-1 E2 DMA-binding domain bound to its DNA target

The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension

BIK, the founding member of the BH3-only family proteins: mechanisms of cell death and role in cancer and pathogenic processes

Author Correction: Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48

A direct and melanopsin-dependent fetal light response regulates mouse eye development

Eyes absent represents a class of protein tyrosine phosphatases

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

An opsin 5–dopamine pathway mediates light-dependent vascular development in the eye

The crystal structure of the bacterial chaperonln GroEL at 2.8 Å

The Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cells

Advancing educational data mining for enhanced student performance prediction: a fusion of feature selection algorithms and classification techniques with dynamic feature ensemble evolution

Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48

Novel and recurrent CIB2 variants, associated with nonsyndromic deafness, do not affect calcium buffering and localization in hair cells

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