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Showing 1–3 of 3 results
Advanced filters: Author: Regina Bohn Clear advanced filters

  • During meiosis the MRX complex is required for DSB formation in budding yeast. Here, the authors show the Mre11 forms DNA-dependent condensates via its C-terminal disordered tail, which further interacts with Mer2 and Smt3, enabling MRX recruitment to chromatin and programmed DSB formation during meiosis.

    • Priyanka Priyadarshini
    • Mahesh Survi
    • Corentin Claeys Bouuaert
    ResearchOpen Access
    Nature Communications
    P: 1-17

  • Conditional ablation experiments show that key components of the synaptonemal complex protect double Holliday junction recombination intermediates to ensure their resolution into crossover products, which are required for accurate chromosome segregation during meiosis.

    • Shangming Tang
    • Sara Hariri
    • Neil Hunter
    ResearchOpen Access
    Nature
    Volume: 647, P: 776-785