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Showing 1–3 of 3 results
Advanced filters: Author: Richard P. Halley-Stott Clear advanced filters

  • Differentiated cells can become pluripotent through reprogramming by nuclear transfer, cell fusion and induced pluripotent stem cell technology. The characteristics of reprogramming by nuclear transfer and cell fusion suggest that they occur in a deterministic, rather than a stochastic, manner.

    • Jerome Jullien
    • Vincent Pasque
    • J. B. Gurdon
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 12, P: 453-459

  • This study shows that PADI4-mediated citrullination occurs during pluripotency and that citrullination of H1 results in loosening of chromatin compaction; furthermore, citrullination is shown to be important for the activation of stem-cell genes, for iPS cell reprogramming and to maintain pluripotent cells in the early mouse embryo.

    • Maria A. Christophorou
    • Gonçalo Castelo-Branco
    • Tony Kouzarides
    Research
    Nature
    Volume: 507, P: 104-108