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Showing 1–8 of 8 results

Advanced filters: Author: Roberto Contestabile Clear advanced filters

Tumor suppressor function of SHMT in a Drosophila Ras^V12Dlg^RNAi model: DNA damage and synergistic gene-nutrient interaction with PLP

Chiara Angioli
Angelo Ferriero
Fiammetta Vernì
ResearchOpen Access26 Mar 2026
Cell Death & Disease

P: 1-14
One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse

With structural models now available on a proteome scale, Malatesta et al. show that structure-based screening can help identify proteins catalyzing orphan reactions in metabolic pathways, offering functional insights beyond sequence-based approaches.

Marco Malatesta
Emanuele Fornasier
Riccardo Percudani
ResearchOpen Access13 Apr 2024
Nature Communications

Volume: 15, P: 1-16
RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation

Francesca Romana Liberati
Sharon Spizzichino
Francesca Cutruzzolà
ResearchOpen Access06 Aug 2025
Cell Death Discovery

Volume: 11, P: 1-10
Molecular characterization of pyridoxine 5′-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy

Anna Barile
Isabel Nogués
Angela Tramonti
ResearchOpen Access12 Aug 2020
Scientific Reports

Volume: 10, P: 1-15
Structural basis of methotrexate and pemetrexed action on serine hydroxymethyltransferases revealed using plant models

Milosz Ruszkowski
Bartosz Sekula
Zbigniew Dauter
ResearchOpen Access23 Dec 2019
Scientific Reports

Volume: 9, P: 1-14
The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity

Elisa Mascolo
Anna Barile
Fiammetta Vernì
ResearchOpen Access02 Oct 2019
Scientific Reports

Volume: 9, P: 1-10
Vitamin B6 deficiency cooperates with oncogenic Ras to induce malignant tumors in Drosophila

Eleonora Pilesi
Giulia Tesoriere
Fiammetta Vernì
ResearchOpen Access03 Jun 2024
Cell Death & Disease

Volume: 15, P: 1-13
Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis

Garik Mkrtchyan
Vasily Aleshin
Victoria Bunik
ResearchOpen Access27 Jul 2015
Scientific Reports

Volume: 5, P: 1-26