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Circular single stranded DNA potentiates non-viral gene insertion in hematopoietic stem and progenitor cells

Letort et al. demonstrate that Circular single-stranded DNA enables efficient and precise gene insertion in hematopoietic stem cells, outperforming other DNA delivery formats and supporting progress toward scalable next-generation gene therapies.

Gil Letort
Aymeric Duclert
Julien Valton
ResearchOpen Access19 Nov 2025
Nature Communications

Volume: 16, P: 1-12
Distribution of two distinct Ca²⁺ -ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaff in cells

Robert D. Burgoyne
Timothy R. Cheek
J. Malcolm East
Research02 Nov 1989
Nature

Volume: 342, P: 72-74
Aim-less translation: loss of Saccharomyces cerevisiae mitochondrial translation initiation factor mIF3/Aim23 leads to unbalanced protein synthesis

Anton Kuzmenko
Ksenia Derbikova
Vasili Hauryliuk
ResearchOpen Access05 Jan 2016
Scientific Reports

Volume: 6, P: 1-9
A caspase-2-RFXANK interaction and its implication for MHC class II expression

Jeremy Forsberg
Xinge Li
Magnus Olsson
ResearchOpen Access23 Jan 2018
Cell Death & Disease

Volume: 9, P: 1-11