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Showing 1–25 of 25 results
Advanced filters: Author: Ron Milo Clear advanced filters

  • Here, the authors estimate mammalian biomass from the 1850’s to today, tracking an increase of over five-fold in human and domesticated mammal biomass and a two-fold decrease in wild mammal biomass. Recent trends of increase in some wild marine mammals are seen to be still far below historic levels. The results of this study are caveated due to limited historic data but have implications for conservation efforts.

    • Lior Greenspoon
    • Noam Ramot
    • Ron Milo
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-7

  • Estimates of global total biomass (the mass of all living things) and anthopogenic mass (the mass embedded in inanimate objects made by humans) over time show that we are roughly at the timepoint when anthropogenic mass exceeds total biomass.

    • Emily Elhacham
    • Liad Ben-Uri
    • Ron Milo
    Research
    Nature
    Volume: 588, P: 442-444

  • Quantifying the global estimated movement of biomass on Earth, the authors show that land animal biomass movement is around 40 times smaller than all human biomass movement, with marine animal movement of biomass having halved since 1850.

    • Yuval Rosenberg
    • Dominik Wiedenhofer
    • Ron Milo
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 9, P: 2259-2264

  • A comprehensive census of the dynamics of death and regeneration of cells and tissues provides an estimation of the distribution of cellular turnover in the human body.

    • Ron Sender
    • Ron Milo
    Research
    Nature Medicine
    Volume: 27, P: 45-48

  • The US beef industry is regarded as environmentally unsustainable. Modelling a system where cattle subsist solely on grass and food industry by-products, the authors estimate that 45% of current production could be achieved without the use of any high quality cropland.

    • Gidon Eshel
    • Alon Shepon
    • Ron Milo
    Research
    Nature Ecology & Evolution
    Volume: 2, P: 81-85

  • Genetically identical cells produce variable levels of a given protein at a given time, termed 'noise' in gene expression. The dynamics of such noise over time has now been followed in human cancer cells. The work reveals surprisingly long-lasting 'memories' of individual cell states, which can last for more than two generations in culture.

    • Alex Sigal
    • Ron Milo
    • Uri Alon
    Research
    Nature
    Volume: 444, P: 643-646

  • Producing goods, such as foods and fuels, with minimal environmental impacts is urgently needed. Although advances in bioproduction are promising, there is often a noticeable gap in our understanding of whether and where new processes can compete with existing methods on an economic and environmental basis. Transparent lower bound calculations from basic principles highlight potential benefits of producing foods, but not fuels, from electro-microbial production of biomass.

    • Samuel J. Lovat
    • Roee Ben-Nissan
    • Ron Milo
    Comments & Opinion
    Nature Biotechnology
    Volume: 43, P: 848-853

  • A massively parallel assay developed to map the essential photosynthetic enzyme rubisco showed that non-trivial biochemical changes and improvements in CO2 affinity are possible, signposting further enzyme engineering efforts to increase crop yields.

    • Noam Prywes
    • Naiya R. Phillips
    • David F. Savage
    ResearchOpen Access
    Nature
    Volume: 638, P: 823-828

  • An E. coli strain able to use CO2 fixation for sugar synthesis was previously generated by experimental evolution of an engineered strain. Here, Herz et al. show that specific mutations in five genes, encoding carbon metabolism enzymes or key regulators, are sufficient to enable robust growth of the strain.

    • Elad Herz
    • Niv Antonovsky
    • Ron Milo
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-10

  • Biofilms are a fundamental form of microbial life and occur in diverse environments, ranging from the mammalian gut to deep subsurface rocks. It is often claimed that most bacteria and archaea live in biofilms, but this claim awaits quantification. Recent updates on global microbial cell numbers prompt a revisiting of this question.

    • Yinon M. Bar-On
    • Ron Milo
    News & Views
    Nature Reviews Microbiology
    Volume: 17, P: 199-200

  • A study quantifying the neutralization of severe acute respiratory syndrome coronavirus 2 variants in individuals infected with Omicron/BA.1 shows that vaccinated individuals previously infected with Omicron have enhanced protection against reinfection with current variants, \including Omicron/BA.2, while Omicron/BA.1 infected unvaccinated individuals have limited protection.

    • Khadija Khan
    • Farina Karim
    • Alex Sigal
    ResearchOpen Access
    Nature
    Volume: 607, P: 356-359

  • Regulatory B (Breg) cells suppress excessive inflammation primary via the production of interleukin 10 (IL-10). Here the authors show that the function and homeostasis of mouse and human IL-10+ Breg cells are negatively regulated by the cell surface receptor, SLAMF5, to impact experimental autoimmunity, thereby hinting SLAMF5 as a potential target for immunotherapy.

    • Lihi Radomir
    • Matthias P. Kramer
    • Idit Shachar
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14

  • Patient data from the Israeli Ministry of Health demonstrates that a 3rd dose of BNT162b2 is effective in reducing Omicron BA.1/BA.2 severe disease and does not wane over the seven month study period as well as that a fourth dose further improves the protective features of vaccination.

    • Ofra Amir
    • Yair Goldberg
    • Ron Milo
    ResearchOpen Access
    Communications Biology
    Volume: 6, P: 1-7

  • The framework presented in the Dublin Declaration has generated controversy by advocating for maintaining or increasing livestock numbers. The serious and acute harms associated with global livestock production today bring the goals of the declaration into dispute.

    • Chris Bryant
    • Harry Aiking
    • Hannah van Zanten
    Comments & Opinion
    Nature Food
    Volume: 5, P: 799-801

  • Unambiguous metabolite annotation is a critical, yet problematic step, in mass spectrometry based metabolomics. Here, Shahaf et al. present WEIZMASS, a platform consisting of a diverse spectral library of more than 3500 plant metabolites and software to aid their identification in biological samples.

    • Nir Shahaf
    • Ilana Rogachev
    • Asaph Aharoni
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-13

  • The Omicron variant of SARS-CoV-2 has been reported to cause milder disease in adults but lead to increased hospital admissions in children. How can we compare disease severity in Omicron and Delta infections, and how should differences be interpreted?

    • Alex Sigal
    • Ron Milo
    • Waasila Jassat
    Comments & Opinion
    Nature Reviews Immunology
    Volume: 22, P: 267-269