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Showing 1–7 of 7 results
Advanced filters: Author: Rory Nolan Clear advanced filters

  • A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

    • Antonia Ho
    • Richard Orton
    • Emma C. Thomson
    Research
    Nature
    Volume: 617, P: 555-563

  • The molecular etiology of hypertensive disorders of pregnancy is largely unknown. Here the authors show from a prospective study of diverse pregnancies that the disease can be split into molecular subtypes based on RNA data and validated a classifier for individuals with no preexisting high risk factors.

    • Michal A. Elovitz
    • Elaine P. S. Gee
    • Morten Rasmussen
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • The interactions between HIV-1 Env and host cell receptors CD4 and CCR5 or CXCR4 are examined using direct stochastic optical reconstruction microscopy and fluorescence fluctuation spectroscopy imaging, revealing a dynamic three-step process leading to formation of the pre-fusion complex.

    • Maro Iliopoulou
    • Rory Nolan
    • Sergi Padilla-Parra
    Research
    Nature Structural & Molecular Biology
    Volume: 25, P: 814-822

  • The UK Biobank combines detailed phenotyping and genotyping with tracking of long-term health outcomes in a large cohort. This study describes the recently launched brain-imaging component that will ultimately scan 100,000 individuals. Results from the first 5,000 subjects are reported, including thousands of associations, population modes and hypothesis-driven results.

    • Karla L Miller
    • Fidel Alfaro-Almagro
    • Stephen M Smith
    Research
    Nature Neuroscience
    Volume: 19, P: 1523-1536