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Showing 1–47 of 47 results

Advanced filters: Author: S Le Gouill Clear advanced filters

A pivotal role for Mcl-1 in Bortezomib-induced apoptosis

K Podar
S L Gouill
K C Anderson
Research23 Jul 2007
Oncogene

Volume: 27, P: 721-731
Multiple intramolecular triggers converge to preferential G protein coupling in the CB₂R

Nonselective engagement of GPCR signaling pathways by GPCR-targeting drugs can reduce treatment efficacy and cause side effects. The authors show that signaling selectivity in CB2R can be tuned by reshaping allosteric networks, offering insights for more precise therapies.

Adrian Morales-Pastor
Tamara Miljuš
Jana Selent
ResearchOpen Access11 Jun 2025
Nature Communications

Volume: 16, P: 1-14
Allogeneic hematopoietic stem cell transplantation for patients with relapsed/refractory systemic anaplastic large cell lymphoma. A retrospective analysis of the Lymphoma Working Party of the European Society for Blood and Marrow Transplantation

E. Domingo-Domènech
A. Boumendil
P. Dreger
Research06 Nov 2019
Bone Marrow Transplantation

Volume: 55, P: 633-640
Potentiation of mitochondrial function by mitoDREADD-G_s reverses pharmacological and neurodegenerative cognitive impairment in mice

Activation of G_s signaling at mitochondria by mitoDREADD-G_s increases mitochondrial metabolism, leading to better memory in mouse models of dementia, directly linking brain mitochondrial deficits to cognitive symptoms of neurodegenerative diseases.

Antonio C. Pagano Zottola
Rebeca Martín-Jiménez
Etienne Hebert-Chatelain
Research11 Aug 2025
Nature Neuroscience

Volume: 28, P: 1844-1857
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics

Agonists of the glucagon-like peptide-1 receptor are used to treat diabetes and obesity. Here, Wright et al. investigate the subcellular location of the receptor’s signaling events and uncover associations between signaling profiles and adverse drug reactions.

Shane C. Wright
Aikaterini Motso
Volker M. Lauschke
ResearchOpen Access09 Oct 2023
Nature Communications

Volume: 14, P: 1-13
Allogeneic transplantation following a reduced-intensity conditioning regimen in relapsed/refractory peripheral T-cell lymphomas: long-term remissions and response to donor lymphocyte infusions support the role of a graft-versus-lymphoma effect

A Dodero
F Spina
P Corradini
Research09 Sept 2011
Leukemia

Volume: 26, P: 520-526
Non-myeloablative allogeneic hematopoietic stem cell transplantation for adults with relapsed and refractory mantle cell lymphoma: a single-center analysis in the rituximab era

A Mussetti
S M Devlin
M-A Perales
Research06 Jul 2015
Bone Marrow Transplantation

Volume: 50, P: 1293-1298
Anti-thymocyte globulin could improve the outcome of allogeneic hematopoietic stem cell transplantation in patients with highly aggressive T-cell tumors

J Yang
Y Cai
C Wang
ResearchOpen Access31 Jul 2015
Blood Cancer Journal

Volume: 5, P: e332
A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

Beta-arrestins play central roles in the mechanisms regulating GPCR signalling and trafficking. Here the authors identify a selective inhibitor of the interaction between β-arrestin and the β2-adaptin subunit of the clathrin adaptor protein AP-2, which they use to dissect the role of the β-arrestin/β2-adaptin interaction in GPCR signalling.

Alexandre Beautrait
Justine S. Paradis
Michel Bouvier
ResearchOpen Access18 Apr 2017
Nature Communications

Volume: 8, P: 1-16
Escalated lymphodepletion followed by donor lymphocyte infusion can induce a graft-versus-host response without overwhelming toxicity

T Guillaume
B Gaugler
M Mohty
Research28 Nov 2011
Bone Marrow Transplantation

Volume: 47, P: 1112-1117
Graft-versus-T-cell lymphoma effect: a sustained CR after tapering immunosuppressive drugs in a patient with angioimmunoblastic T-cell lymphoma in relapse after allogeneic transplantation

A C Mamez
L Souchet
S Nguyen
Correspondence03 Nov 2014
Bone Marrow Transplantation

Volume: 50, P: 304-306
BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma

L Bodet
E Ménoret
P Gomez-Bougie
ResearchOpen Access09 Nov 2010
British Journal of Cancer

Volume: 103, P: 1808-1814
Farnesyl transferase inhibitor R115777 induces apoptosis of human myeloma cells

S Le Gouill
C Pellat-Deceunynck
M Amiot
Research30 Aug 2002
Leukemia

Volume: 16, P: 1664-1667
Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs

V Ramakrishnan
M Timm
S Kumar
Research23 Nov 2009
Oncogene

Volume: 29, P: 1190-1202
Evidence of a role for the novel zinc-finger transcription factor ZKSCAN3 in modulating Cyclin D2 expression in multiple myeloma

L Yang
H Wang
R Z Orlowski
Research08 Nov 2010
Oncogene

Volume: 30, P: 1329-1340
Epidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancer

E P Booy
E S Henson
S B Gibson
ResearchOpen Access24 Jan 2011
Oncogene

Volume: 30, P: 2367-2378
Effect of graft source on mismatched unrelated donor hemopoietic stem cell transplantation after reduced intensity conditioning

F Malard
S Fürst
M Mohty
Research11 Jun 2013
Leukemia

Volume: 27, P: 2113-2117
Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival

S Wuillème-Toumi
N Robillard
R Bataille
Research05 May 2005
Leukemia

Volume: 19, P: 1248-1252
Azacitidine salvage therapy for relapse of myeloid malignancies following allogeneic hematopoietic SCT

B Tessoulin
J Delaunay
T Guillaume
Research03 Feb 2014
Bone Marrow Transplantation

Volume: 49, P: 567-571
Impact of high-dose chemotherapy followed by auto-SCT for positive interim [¹⁸F] FDG-PET diffuse large B-cell lymphoma patients

V Roland
C Bodet-Milin
S Le Gouill
Research31 May 2010
Bone Marrow Transplantation

Volume: 46, P: 393-399
Paradoxical effect of lenalidomide on cytokine/growth factor profiles in multiple myeloma

S Maïga
P Gomez-Bougie
M Amiot
ResearchOpen Access30 Apr 2013
British Journal of Cancer

Volume: 108, P: 1801-1806
Features of EBV reactivation after reduced intensity conditioning unrelated umbilical cord blood transplantation

Z Peric
X Cahu
M Mohty
Research28 Mar 2011
Bone Marrow Transplantation

Volume: 47, P: 251-257
The outcome of reduced intensity allogeneic stem cell transplantation and autologous stem cell transplantation when performed as a first transplant strategy in relapsed follicular lymphoma: an analysis from the Lymphoma Working Party of the EBMT

S P Robinson
C Canals
A Sureda
Research17 Jun 2013
Bone Marrow Transplantation

Volume: 48, P: 1409-1414
Radioimmunotherapy-augmented BEAM chemotherapy vs BEAM alone as the high-dose regimen for autologous stem cell transplantation (ASCT) in relapsed follicular lymphoma (FL): a retrospective study of the EBMT Lymphoma Working Party

L Bento
A Boumendil
S Montoto
Research22 May 2017
Bone Marrow Transplantation

Volume: 52, P: 1120-1125
Adult lymphoblastic lymphoma: a retrospective analysis of 92 patients under 61 years included in the LNH87/93 trials

S Le Gouill
S Lepretre
P Brice
Research24 Oct 2003
Leukemia

Volume: 17, P: 2220-2224
Mitochondria in hematopoiesis and hematological diseases

M Fontenay
S Cathelin
E Solary
Reviews07 Aug 2006
Oncogene

Volume: 25, P: 4757-4767
Combination of lenalidomide with vitamin D3 induces apoptosis in mantle cell lymphoma via demethylation of BIK

C Brosseau
C Dousset
C Pellat-Deceunynck
ResearchOpen Access28 Aug 2014
Cell Death & Disease

Volume: 5, P: e1389
The role of hematopoietic SCT in adult Burkitt lymphoma

S O Ahmed
A Sureda
M Aljurf
Reviews30 Jul 2012
Bone Marrow Transplantation

Volume: 48, P: 617-629
Post-autologous transplant maintenance therapies in lymphoid malignancies: are we there yet?

N Epperla
T S Fenske
M Hamadani
Reviews17 Aug 2015
Bone Marrow Transplantation

Volume: 50, P: 1393-1404
Is myeloablative dose intensity necessary in allogeneic hematopoietic cell transplantation for lymphomas?

M A Kharfan-Dabaja
N El-Jurdi
M Hamadani
Reviews03 Apr 2017
Bone Marrow Transplantation

Volume: 52, P: 1487-1494
Safety and efficacy of rituximab in steroid-refractory chronic GVHD

A Clavert
P Chevallier
M Mohty
Correspondence22 Oct 2012
Bone Marrow Transplantation

Volume: 48, P: 734-736
Features of Epstein-Barr Virus (EBV) reactivation after reduced intensity conditioning allogeneic hematopoietic stem cell transplantation

Z Peric
X Cahu
M Mohty
Research25 Feb 2011
Leukemia

Volume: 25, P: 932-938
FISH for BCR-ABL on interphases of peripheral blood neutrophils but not of unselected white cells correlates with bone marrow cytogenetics in CML patients treated with imatinib

U Reinhold
E Hennig
M W N Deininger
Comments & Opinion26 Sept 2003
Leukemia

Volume: 17, P: 1925-1929
Is CAR T a drug or a therapeutic pathway? Intention to treat versus per protocol analysis of real world studies of CAR-T cell therapy in relapsed refractory diffuse large B cell lymphoma

Rossana Di Staso
Beatrice Casadei
Lisa Argnani
CorrespondenceOpen Access07 Nov 2024
Blood Cancer Journal

Volume: 14, P: 1-5
The cap-translation inhibitor 4EGI-1 induces apoptosis in multiple myeloma through Noxa induction

G Descamps
P Gomez-Bougie
M Amiot
ResearchOpen Access17 Apr 2012
British Journal of Cancer

Volume: 106, P: 1660-1667
High level of soluble programmed cell death ligand 1 in blood impacts overall survival in aggressive diffuse large B-Cell lymphoma: results from a French multicenter clinical trial

D Rossille
M Gressier
P Godemer
Research15 Apr 2014
Leukemia

Volume: 28, P: 2367-2375
Second-degree relative donors for T-replete haploidentical allogeneic stem cell transplantation with high-dose post-transplant cyclophosphamide: toward crossing the major HLA barrier

A Garnier
T Guillaume
P Chevallier
Correspondence03 Apr 2017
Bone Marrow Transplantation

Volume: 52, P: 1063-1064
Prophylaxis with mycophenolate mofetil and CsA can decrease the incidence of severe acute GVHD after antithymocyte globulin-based reduced-intensity preparative regimen and allo-SCT from HLA-matched unrelated donors

E Brissot
P Chevallier
M Mohty
Correspondence31 Aug 2009
Bone Marrow Transplantation

Volume: 45, P: 786-788
Impact of lenalidomide on immune functions in the setting of maintenance therapy for multiple myeloma

E Brissot
A Clavert
M Mohty
Correspondence09 Mar 2015
Leukemia

Volume: 29, P: 2098-2100
BH3 profiling identifies heterogeneous dependency on Bcl-2 family members in multiple myeloma and predicts sensitivity to BH3 mimetics

C Touzeau
J Ryan
A Letai
Correspondence15 Jul 2015
Leukemia

Volume: 30, P: 761-764
Lack of BRAF V600E mutation in human myeloma cell lines established from myeloma patients with extramedullary disease

L Lodé
P Moreau
C Pellat-Deceunynck
CorrespondenceOpen Access22 Nov 2013
Blood Cancer Journal

Volume: 3, P: e163
Factors predicting allogeneic PBSCs yield after G-CSF treatment in healthy donors

E Brissot
P Chevallier
M Mohty
Correspondence23 Mar 2009
Bone Marrow Transplantation

Volume: 44, P: 613-615
The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma

C Touzeau
C Dousset
M Amiot
CorrespondenceOpen Access17 Jul 2013
Leukemia

Volume: 28, P: 210-212
Autocrine insulin-like growth factor 1 and stem cell factor but not interleukin 6 support self-renewal of human myeloma cells

D Chiron
S Maïga
C Pellat-Deceunynck
ResearchOpen Access07 Jun 2013
Blood Cancer Journal

Volume: 3, P: e120
Allogeneic stem cell transplantation for patients with mantle cell lymphoma who failed autologous stem cell transplantation: a national survey of the SFGM-TC

B Tessoulin
P Ceballos
S Le Gouill
Research25 Apr 2016
Bone Marrow Transplantation

Volume: 51, P: 1184-1190
The EBMT/EMCL consensus project on the role of autologous and allogeneic stem cell transplantation in mantle cell lymphoma

S Robinson
P Dreger
O Hermine
Research18 Jul 2014
Leukemia

Volume: 29, P: 464-473
Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: identification of potential disease-specific targets

A Maiga
S Lemieux
J Hébert
ResearchOpen Access03 Jun 2016
Blood Cancer Journal

Volume: 6, P: e431

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