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‘Populations residing near nuclear power plants may experience low-level chronic exposure to ionizing radiation through environmental release pathways. In here the authors find higher cancer mortality rates in U.S. counties closer to operational nuclear power plants, with the strongest relative risks observed in older adults.’

Africa is stepping up in planning and constructing power plants up to 2030 with renewables’ share growing from 19% to 34%. An inventory of 3139 plants forecasts a 57% increase in electricity production with water use increasing 73% and CO₂ 19%.

Unlike animals, plant possess mitochondria and chloroplasts and exhibit a unique defensive adaptation to stress. Here, the authors demonstrate the feasibility of restoring organelle interaction network homeostasis in animal cells by introducing plant-derived photosynthetic systems.

Protein coacervates have potential as force generators, but this remains an underexplored area. Here, the authors report the development of an elastin-based protocell model with temperature controlled contractility and attendant force harnessing, allowing control of protocell dynamics.

Understanding the structural origins of stability in disordered solids is essential for predicting mechanical failure and manipulating their properties, yet the inherent disorder complicates this analysis. This study identifies stabilizing bonds as critical structural features that govern stability across a spectrum from marginal to ultra-stable disordered solids, providing a unified framework for understanding their mechanical behavior.

Formamidine-based perovskite solar cells promise high efficiency, but additive-induced deprotonation disrupts precursor stability and device performance. Dong et al. use a hydrolyzing ester additive to regulate proton transfer, stabilizing the precursor and achieve efficient, durable devices.

Researchers demonstrate field-free magnetisation switching in perpendicular magnetic anisotropy systems using spin reorientation and orbital Hall effects. This approach enables low power operation and scalable spintronic memory devices.

Global analysis of obesity trends from 1980 to 2024 in 200 countries and territories using data from 4,050 population-based studies reveals that framing obesity as a single global epidemic masks the highly varied dynamics across countries and age groups.

Electrochromic displays offer low power consumption, but achieving large-area stretchability with high pixel resolution remains challenging. Kim et al. demonstrate a photo-patternable stretchable device enabling 10 × 10 cm² RGB pixelated display with stable performance under repeated strain.

A measurement of the hyperfine splitting energy of the ground state of antihydrogen at 4 ppm precision reaches a point at which this result is sensitive to the internal structure of the antiproton.

Genome-wide analyses in multiancestry and European cohorts show that in complex traits, rare alleles have disproportionately large effects at the tails of the phenotypic spectrum compared with common alleles.

Intracranial recordings in children revealed neural signals predicting attentional lapses. Closed-loop stimulation rescued performance and scalp EEG enabled noninvasive modulation, identifying a reproducible marker of attentional control.

How the brain supports speaking and listening during conversation of its natural form remains poorly understood. Here, by combining intracranial EEG recordings with Natural Language Processing, the authors show broadly distributed frontotemporal neural signals that encode context-dependent linguistic information during both speaking and listening..

A wearable ultrasound device is optimized for continuous monitoring of pregnancies.

MOSAIC is a versatile multimodal microscope that allows seamless transition between various light-sheet, two-photon, label-free and super-resolution modalities. It is demonstrated in various systems ranging from cell culture to mice.

H3K27-altered diffuse midline gliomas are a highly aggressive form of paediatric brain cancer. Here, the authors present molecular profiling of 68 patients, and show the efficacy of precision-guided therapy based on this profiling.

Mizrak et al. use single-molecule tracking to dissect mechanisms of protein targeting to lipid droplets. They show that nanodomain-based confinement drives selective protein accumulation on lipid droplets.

The authors observe re-entrant superconductivity beyond a superconductor-to-insulator transition in a granular aluminum thin-film nanobridge, which they demonstrate functions as naturally occurring Josephson junction array. They argue that the re-entrant behavior is induced by the screening of electron charge, a many-body correlation effect.

Interferometric scattering microscopy combined with photoluminescence imaging enables the fast, high-throughput screening of size and quantum yield for thousands of perovskite nanocubes at the single-particle level across their entire life cycle.

An on-chip light-programmable valley optoelectronic nanocircuit enabled by meta-waveguide photodetectors integrated with transition metal dichalcogenides is demonstrated. In situ generation, selective routing and electrical readout of valley-dependent chiral photons are achieved.

Integration of gene expression data from multiple tissues across four mammalian species reveals conserved transcriptomic signatures of mammalian ageing and mortality and uncovers the modular architecture of ageing and mortality hallmarks.

Multi-ancestry exome-wide analyses in the Million Veteran Program, UK Biobank and All of Us identify rare coding variants across 209 genes associated with blood lipid traits, highlighting new candidate drug targets across diverse populations.

Exercise-mediated neuroprotection in a mouse model of multiple sclerosis is reduced in mice lacking the irisin-encoding gene, Fndc5, and can be recapitulated by peripheral administration of irisin.

The annealing process introduces strain into the perovskite and undermines the stability of the solar cells. Xiaofeng Gao et al. address this issue by using a meltable additive, 1,4-butanesultam, to relieve strain and improve operational stability.

Chromatin dynamics govern search times between DNA elements. Using integrated MINFLUX imaging, Mazzocca, Narducci, Grosse-Holz and colleagues track chromatin dynamics over seven orders of magnitude in time, revealing two dynamics classes and providing bounds on search times.

Ageing impairs strategic re-aiming but enhances implicit recalibration during sensorimotor learning. The strategic deficit probably reflects reduced memory caching, whereas the implicit enhancement is linked to altered multisensory integration.

SIGnature enables scalable cross-dataset analyses by combining explainable artificial intelligence with RNA foundation models.

NG101 treatment for acute cervical spinal cord injury mitigates structural degeneration compared to placebo. Stratifying patients via MRI and electrophysiology identifies clinical responder subgroups, optimizing future trial designs.

Using xenograft inflammation–recovery models and single-cell multiomics, a haematopoietic stem cell population after inflammatory stress is identified.

Triplet tetrylenes are typically too short-lived for detailed investigation. Now a triplet germylene with a 14-h half-life at 25 °C has been generated through photoexcitation of a germylene compound, enabling spectroscopic characterization and probing of its reactivity.

This Commission aims to resolve the current dialysis policy challenges in Thailand and generate lessons for the global kidney community by drawing on empirical evidence, systems thinking and multidisciplinary expertise to generate policy goals and recommendations.

The risk of chronic health conditions attributed to lifestyle factors in childhood cancer survivors is not clear. Here, the authors report that significant proportion of chronic health conditions in childhood cancer survivors could be attributed to lifestyle.

In a multicenter phase 2 trial, the fibroblast growth factor receptor inhibitor rogaratinib showed encouraging clinical efficacy in patients with succinate dehydrogenase-deficient gastrointestinal stromal tumors, suggesting a potential new treatment option for this patient population and demonstrating that an epigenetic mechanism of oncogene activation can be successfully targeted with a tyrosine kinase inhibitor.

Compiling data on floral introductions and European colonial history of regions worldwide, the authors find that compositional similarity of floras is higher than expected among regions once occupied by the same empire and similarity increases with the length of time the region was occupied by that empire.

Atallah et al. show that oxidized phospholipids and lipoprotein (a), but not systemic inflammation indicators are associated with tissue-level myocardial inflammation after infarction.

An annular carbon-nanotube nanosensor array integrated onto a medical-grade catheter enables near-infrared, in situ spatial mapping of bladder cancer-associated protein biomarker release in the bladder with 182-fold higher sensitivity than urine sampling.