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Advanced filters: Author: S. Akila Parvathy Dharshini Clear advanced filters

Molecular signatures of resilience to Alzheimer’s disease in neocortical layer 4 neurons

Using single-nucleus and spatial transcriptomics, the authors reveal resilience signatures in neocortical layer 4 neurons. They show KCNIP4 protects these cells by reducing hyperexcitability, a driver of neurodegeneration.

S. Akila Parvathy Dharshini
Jorge Sanz-Ros
Inma Cobos
ResearchOpen Access31 Jan 2026
Nature Communications

P: 1-23
Investigating the energy crisis in Alzheimer disease using transcriptome study

S. Akila Parvathy Dharshini
Y.-h. Taguchi
M. Michael Gromiha
ResearchOpen Access06 Dec 2019
Scientific Reports

Volume: 9, P: 1-13

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Molecular signatures of resilience to Alzheimer’s disease in neocortical layer 4 neurons

Investigating the energy crisis in Alzheimer disease using transcriptome study

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