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Showing 51–100 of 159 results

Advanced filters: Author: S. Klee Clear advanced filters

A transient outward current in a mammalian central neurone blocked by 4-aminopyridine

B. Gustafsson
M. Galvan
H. Wigström
Research16 Sept 1982
Nature

Volume: 299, P: 252-254
Effect of Acetoxycycloheximide on Learning and Memory of a Light–Dark Discrimination

H. D. COHEN
S. H. BARONDES
Research20 Apr 1968
Nature

Volume: 218, P: 271-273
Surface membrane alterations in somatic cell hybrids of neuroblastoma and glioma cells

MARY CATHERINE GLICK
YOSEF KIMHI
URIEL Z. LITTAUER
Research22 Jan 1976
Nature

Volume: 259, P: 230-232
Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction

Endothelial cells play a critical role in the adaptation of tissues to injury and show a remarkable plasticity. Here the authors show, using single cell sequencing, that endothelial cells acquire a transient mesenchymal state associated with metabolic adaptation after myocardial infarction.

Lukas S. Tombor
David John
Stefanie Dimmeler
ResearchOpen Access29 Jan 2021
Nature Communications

Volume: 12, P: 1-12
Meta-analysis of genome-wide association studies provides insights into genetic control of tomato flavor

Flavor is one of the most important traits for improving tomato sensory quality and consumer acceptability. Here, the authors report meta-analysis of genome-wide association studies of flavor related traits and show genetic insights into the influence of human selection during domestication and improvement.

Jiantao Zhao
Christopher Sauvage
Mathilde Causse
ResearchOpen Access04 Apr 2019
Nature Communications

Volume: 10, P: 1-12
Correction: The genomic mutation rate for fitness in Drosophila

D. Houle
D. K. Hoffmaster
B. Charlesworth
Amendments and Corrections22 Sept 1994
Nature

Volume: 371, P: 358
Genome-wide detection of tandem DNA repeats that are expanded in autism

Genome-wide analysis of tandem DNA repeats in the genomes of individuals with autism spectrum disorder and control participants reveals a strong contribution of tandem repeat expansions to the genetic aetiology and phenotypic complexity of autism spectrum disorder.

Brett Trost
Worrawat Engchuan
Ryan K. C. Yuen
Research27 Jul 2020
Nature

Volume: 586, P: 80-86
Calcium and calmodulin in Kyoto

Robert S. Adelstein
News & Views24 Dec 1981
Nature

Volume: 294, P: 693-694
Hepatic non-parenchymal S100A9-TLR4-mTORC1 axis normalizes diabetic ketogenesis

Excess ketogenesis can lead to ketoacidosis, a serious complication in patients with diabetes. Here the authors report an insulin independent pathway, the hepatic nonparenchymal S100A9-TLR4-mTORC1 axis, that is able to normalize diabetic ketogenesis and pre-clinical data to suggest potential for development of S100A9 based adjunctive therapy to insulin.

Gloria Ursino
Giorgio Ramadori
Roberto Coppari
ResearchOpen Access15 Jul 2022
Nature Communications

Volume: 13, P: 1-17
Fast ultraviolet-C photonics: generating and sensing laser pulses on femtosecond timescales

A UV-C source-sensor communication system combines phase-matched second-order processes in nonlinear optical crystals for generation of femtosecond UV-C laser pulses with fast-sensors based on two-dimensional semiconductors.

Benjamin T. Dewes
Tim Klee
Amalia Patané
ResearchOpen Access19 Nov 2025
Light: Science & Applications

Volume: 14, P: 1-10
Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome

SPTBN1 mutations cause a neurodevelopmental syndrome characterized by intellectual disability, language and motor delays, autism, seizures and other features. The variants disrupt βII-spectrin function and disturb cytoskeletal organization and dynamics.

Margot A. Cousin
Blake A. Creighton
Damaris N. Lorenzo
Research01 Jul 2021
Nature Genetics

Volume: 53, P: 1006-1021
Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy

UDP-glucuronic acid is a component of the extracellular matrix. Here, the authors report biallelic variants in the gene encoding UDP-Glucose 6-Dehydrogenase (UGDH) in individuals affected by developmental epileptic encephalopathies that impair UGDH stability, oligomerization, or enzymatic activity in vitro.

Holger Hengel
Célia Bosso-Lefèvre
Bruno Reversade
ResearchOpen Access30 Jan 2020
Nature Communications

Volume: 11, P: 1-16
Sustaining the Food Supply

Robert Fraley
Research01 Jan 1992
Bio/Technology

Volume: 10, P: 40-43
AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders

Genetic variants in ionotropic glutamate receptors have been implicated in neurodevelopmental disorders. Here, the authors report heterozygous de novo mutations in the GRIA2 gene in 28 individuals with intellectual disability and neurodevelopmental abnormalities associated with reduced Ca²⁺ transport and AMPAR currents.”

Vincenzo Salpietro
Christine L. Dixon
Henry Houlden
ResearchOpen Access12 Jul 2019
Nature Communications

Volume: 10, P: 1-16
Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491

J. Parkhill
M. Achtman
B. G. Barrell
Research30 Mar 2000
Nature

Volume: 404, P: 502-506
Cloning differentially expressed mRNAs

Jackson S. Wan
Stephen J. Sharp
Mark G. Erlander
Research01 Dec 1996
Nature Biotechnology

Volume: 14, P: 1685-1691
A nucleotide-flipping mechanism from the structure of human uracil–DNA glycosylase bound to DNA

Geir Slupphaug
Clifford D. Mol
John A. Tainer
Research07 Nov 1996
Nature

Volume: 384, P: 87-92
Quality of life in advanced cancer patients: the impact of sociodemographic and medical characteristics

M S Jordhøy
P Fayers
S Kaasa
ResearchOpen Access13 Nov 2001
British Journal of Cancer

Volume: 85, P: 1478-1485
One health approach based descriptive study on Coxiella burnetii infections in camels and abattoir workers in the United Arab Emirates

Mohamud Sheek-Hussein
Aboma Zewude
Gobena Ameni
ResearchOpen Access10 Apr 2025
Scientific Reports

Volume: 15, P: 1-12
Membrane Characteristics of Bursting Pacemaker Neurones in Aplysia

DONALD S. FABER
MANFRED R. KLEE
Correspondence01 Nov 1972
Nature New Biology

Volume: 240, P: 29-31
Assessment of long-term quality of life in patients with anal carcinomas treated by radiotherapy with or without chemotherapy

A S Allal
M A G Sprangers
J M Kurtz
ResearchOpen Access25 Jun 1999
British Journal of Cancer

Volume: 80, P: 1588-1594
Multidisciplinary treatment of synchronous primary rectal and prostate cancers

Athanasios Colonias
Lloyd Farinash
David S Parda
Reviews01 May 2005
Nature Clinical Practice Oncology

Volume: 2, P: 271-274
Genome-wide meta-analysis identifies eight new susceptibility loci for cutaneous squamous cell carcinoma

The authors perform a meta-analysis of cutaneous squamous cell carcinoma, identifying causal variants within skin-specific regulatory elements.

Kavita Y. Sarin
Yuan Lin
Jiali Han
ResearchOpen Access10 Feb 2020
Nature Communications

Volume: 11, P: 1-8
Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans

Huda Zoghbi and colleagues report that loss of the ATXN1–CIC protein complex in the developing mouse forebrain results in hyperactivity and defects in learning and memory. Loss of Cic in specific brain regions causes social interaction defects, and patients with de novo CIC mutations present signs of hyperactivity, autism spectrum disorder and intellectual disability.

Hsiang-Chih Lu
Qiumin Tan
Huda Y Zoghbi
Research13 Mar 2017
Nature Genetics

Volume: 49, P: 527-536
NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B

The NMR structure of the H2A.Z-H2B histone chaperone, Chz1, reveals electrostatic interactions between Chz1 and the histone pair via a long, irregular chain with two capping helices, and, based on a model, the possibility that Chz1 has a more active role in histone replacement is suggested.

Zheng Zhou
Hanqiao Feng
Yawen Bai
Research20 Jul 2008
Nature Structural & Molecular Biology

Volume: 15, P: 868-869
Classical and quantum simulations of 1+1-dimensional \({{\mathbb{Z}}}_{2}\) gauge theory at finite temperature and density

Simulating lattice gauge theories at finite matter density is a major challenge in nuclear and high-energy physics, with implications for condensed matter physics. Here, the authors show that a sampling approach, which can be used on both classical and quantum computers, can address this challenge in a simple 1+1D \({{\mathbb{Z}}}_{2}\) lattice gauge model.

I-Chi Chen
João C. Getelina
Thomas Iadecola
ResearchOpen Access26 Sept 2025
Communications Physics

Volume: 8, P: 1-12
Order or disorder in the structure of glass?

S.R. Elliott
News & Views24 Dec 1981
Nature

Volume: 294, P: 692-693
WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts

S. Klee
M. Lehmann
M. Königshoff
ResearchOpen Access12 Feb 2016
Scientific Reports

Volume: 6, P: 1-11
Bi-allelic variants in CELSR3 are implicated in central nervous system and urinary tract anomalies

Jil D. Stegmann
Jeshurun C. Kalanithy
Alina C. Hilger
ResearchOpen Access01 Mar 2024
npj Genomic Medicine

Volume: 9, P: 1-12
Cell membrane skeleton: The spread of spectrin

Anthony J. Baines
News & Views03 Feb 1983
Nature

Volume: 301, P: 377-378
The influence of genetics on contemporary art

Dorothy Nelkin
Suzanne Anker
Comments & Opinion01 Dec 2002
Nature Reviews Genetics

Volume: 3, P: 967-971
Viral involvement in Hodgkin's disease: detection of clonal type A Epstein-Barr virus genomes in tumour samples

S Gledhill
A Gallagher
RF Jarrett
Research01 Aug 1991
British Journal of Cancer

Volume: 64, P: 227-232
Teacher Assessed Behavior of Children Prenatally Exposed to Cocaine

V Delaney-Black
C Covington
R J Sokol
Research01 Apr 1999
Pediatric Research

Volume: 45, P: 14
A three-dimensional human neural cell culture model of Alzheimer’s disease

Early-onset familial Alzheimer’s disease mutations induce both amyloid-β and tau pathologies in differentiated human neural stem cells in 3D cultures.

Se Hoon Choi
Young Hye Kim
Doo Yeon Kim
Research12 Oct 2014
Nature

Volume: 515, P: 274-278
Calmodulin supports both inactivation and facilitation of L-type calcium channels

Roger D. Zühlke
Geoffrey S. Pitt
Harald Reuter
Research13 May 1999
Nature

Volume: 399, P: 159-162
Herpes Simplex Virus Infection in Neonates and Infants: Variations in Clinical Practice

N V Raju
V Delaney-Black
B Nordstrom-Klee
Research01 Apr 1999
Pediatric Research

Volume: 45, P: 172
Association between genes regulating neural pathways for quantitative traits of speech and language disorders

Penelope Benchek
Robert P. Igo Jr.
Sudha K. Iyengar
ResearchOpen Access27 Jul 2021
npj Genomic Medicine

Volume: 6, P: 1-11
A regulated auxin minimum is required for seed dispersal in Arabidopsis

The fruits of Arabidopsis thaliana split open (dehisce) along the valve margins, leading to seed dispersal. A transcription factor called INDEHISCENT (IND) is known to be important for differentiation of valve margin cells by an unknown mechanism. IND is now shown to be responsible for the formation of a local auxin minimum, necessary for specification of cells in the dehiscence zone.

Karim Sorefan
Thomas Girin
Lars Østergaard
Research28 May 2009
Nature

Volume: 459, P: 583-586
Skeletal muscle hypertrophy is mediated by a Ca²⁺-dependent calcineurin signalling pathway

Christopher Semsarian
Ming-Jie Wu
Robert M. Graham
Research05 Aug 1999
Nature

Volume: 400, P: 576-581
A pre-Inca pot from underwater ruins discovered in an Andean lake provides a sedimentary record of marked hydrological change

Neal Michelutti
Preston Sowell
John P. Smol
ResearchOpen Access16 Dec 2019
Scientific Reports

Volume: 9, P: 1-10
The Rate of Cerebral Utilization of Glucose, Ketone Bodies, and Oxygen: A Comparative in Vivo Study of Infant and Adult Rats

G Dahlquist
B Persson
Research01 Nov 1976
Pediatric Research

Volume: 10, P: 910-917
Defining the genotypic and phenotypic spectrum of X-linked MSL3-related disorder

Theresa Brunet
Kirsty McWalter
Matias Wagner
ResearchOpen Access11 Nov 2020
Genetics in Medicine

Volume: 23, P: 384-395
Insulin, A Possible Regulator of Ketosis in Newborn and Suckling Rats

Yu-Yan Yeh
Paulus Zee
Research01 Mar 1976
Pediatric Research

Volume: 10, P: 192-197
Survey of the rate of PSA testing in general practice

J Melia
S Moss
ResearchOpen Access28 Aug 2001
British Journal of Cancer

Volume: 85, P: 656-657
Sphincter-sparing surgery after preoperative radiotherapy for low rectal cancers: feasibility, oncologic results and quality of life outcomes

A S Allal
S Bieri
P Gertsch
ResearchOpen Access22 Feb 2000
British Journal of Cancer

Volume: 82, P: 1131-1137
The tomato genome sequence provides insights into fleshy fruit evolution

This paper reports the genome sequence of domesticated tomato, a major crop plant, and a draft sequence for its closest wild relative; comparative genomics reveal very little divergence between the two genomes but some important differences with the potato genome, another important food crop in the genus Solanum.

Shusei Sato
Satoshi Tabata
René M. Klein Lankhorst
ResearchOpen Access30 May 2012
Nature

Volume: 485, P: 635-641
The development of Kraepelin’s mature diagnostic concept of hebephrenia: a close reading of relevant texts of Hecker, Daraszkiewicz, and Kraepelin

Kenneth S. Kendler
Reviews09 Apr 2019
Molecular Psychiatry

Volume: 25, P: 180-193
Gut microbiome is not associated with mild cognitive impairment in Parkinson’s disease

Velma T. E. Aho
Matthias Klee
Gelani Zelimkhanov
ResearchOpen Access06 Apr 2024
npj Parkinson's Disease

Volume: 10, P: 1-6
A randomised, blinded, placebo-controlled, dose escalation study of the tolerability and efficacy of filgrastim for haemopoietic stem cell mobilisation in patients with severe active rheumatoid arthritis

JA Snowden
JC Biggs
PM Brooks
Research03 Dec 1998
Bone Marrow Transplantation

Volume: 22, P: 1035-1041
Symbiotic effectiveness in nodulated red clover

F J Bergersen
P S Nutman
Research01 Aug 1957
Heredity

Volume: 11, P: 175-184

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