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Showing 1–9 of 9 results
Advanced filters: Author: Sachin Malde Clear advanced filters

  • The comparative efficacy of drugs for the management of overactive bladder syndrome (OAB) remains undefined. A new indirect treatment comparison demonstrates similar efficacy of mirabegron versus several antimuscarinic drugs and onabotulinum toxin A in a number of outcome measures. Head-to-head trials of these agents are still required to optimize the management of patients with OAB.

    • Arun Sahai
    • Sachin Malde
    News & Views
    Nature Reviews Urology
    Volume: 14, P: 393-394

  • Personalized decision-making is the ultimate goal of managing men with lower urinary tract symptoms caused by benign prostatic obstruction. Urodynamics can provide valuable information in these patients and a recent multicentre randomized trial has highlighted important findings warranting consideration, as well as indicating that further insights are needed.

    • Sachin Malde
    • Eskinder Solomon
    News & Views
    Nature Reviews Urology
    Volume: 17, P: 607-608

  • Antibiotics are the mainstay prophylaxis and treatment for recurrent urinary tract infections (UTIs). However, antibiotic resistance is rising globally, leading to infections that are harder to treat. In view of this resistance, alternative, non-antibiotic treatments for recurrent UTIs are now being developed; among them, UTI vaccines have shown promising results.

    • Quentin Mak
    • Julian Greig
    • Nicholas Raison
    Comments & Opinion
    Nature Reviews Urology
    Volume: 21, P: 701-702

  • Despite the high prevalence of overactive bladder (OAB) syndrome, its pathophysiology remains poorly understood. Twin studies offer a unique opportunity for studying the genetics of this disorder, but trials are limited by heterogeneous patient populations. Improved understanding of genetic factors in OAB will be vital to developing targeted management.

    • Nicholas Raison
    • Sachin Malde
    • Arun Sahai
    Comments & Opinion
    Nature Reviews Urology
    Volume: 20, P: 61-62

  • In this Review, the authors describe the pathogenesis of uncomplicated urinary tract infections (UTIs). They discuss the need for nonantibiotic treatments and explore the nonantibiotic management options for the prevention and management of recurrent UTI.

    • Néha Sihra
    • Anna Goodman
    • Sachin Malde
    Reviews
    Nature Reviews Urology
    Volume: 15, P: 750-776

  • Across health care, clinicians are increasingly using patient-reported outcome measures (PROMs) to give a voice to patients and to help standardize the assessment of patients for comparison purposes. With this increasing use, the limitations of these PROMs should not be underestimated within the diverse population that we treat.

    • Findlay MacAskill
    • Arun Sahai
    • Tet Yap
    Comments & Opinion
    Nature Reviews Urology
    Volume: 20, P: 1-2

  • Focus on quality of life after prostate cancer is vital to improve patient care. Improved assessment and proactive management of post-treatment functional outcomes is essential. Many aspects of the patients’ aftercare need to be improved in order to set up a clear path following prostatectomy. These improvements will enable a timely and efficient escalation of treatment and ameliorate patients’ survivorship experience.

    • Findlay MacAskill
    • Arun Sahai
    • Sachin Malde
    Comments & Opinion
    Nature Reviews Urology
    Volume: 18, P: 703-704