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Nature Communications (2)
npj Breast Cancer (1)

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Advanced filters: Author: Samira Majjaj Clear advanced filters

Palbociclib and endocrine therapy diminish adaptive anti-tumor immunity in early breast cancer: The NeoRHEA phase 2 study

The NeoRHEA trial showed that treatment with palbociclib and endocrine therapy decreases T cell proliferation and the presence of tissue-resident memory T cells. These results are important for the development of CDK4 selective inhibitors.

Andreas Papagiannis
Samira Majjaj
Michail Ignatiadis
ResearchOpen Access26 Nov 2025
Nature Communications

Volume: 16, P: 1-15
Identification of HER2-positive breast cancer molecular subtypes with potential clinical implications in the ALTTO clinical trial

The clinical implications of molecular heterogeneity in HER2-positive breast cancer remain to be explored. Here, the authors investigate the transcriptomic landscape of HER2-positive breast cancer patients receiving adjuvant trastuzumab in the ALTTO clinical trial and identify five distinct molecular subtypes.

Mattia Rediti
David Venet
Christos Sotiriou
ResearchOpen Access29 Nov 2024
Nature Communications

Volume: 15, P: 1-17
Breast cancer diagnosed during pregnancy is associated with enrichment of non-silent mutations, mismatch repair deficiency signature and mucin mutations

Bastien Nguyen
David Venet
Christos Sotiriou
ResearchOpen Access06 Aug 2018
npj Breast Cancer

Volume: 4, P: 1-7

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