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Showing 1–2 of 2 results
Advanced filters: Author: Sara Sanz Juste Clear advanced filters
  • Current sterile insect approaches require labor-intensive sorting. Here, authors develop a temperature-controlled Cas12a system in Drosophila that produces sterile males and eliminates females, offering a scalable genetic tool for controlling pests and disease vectors.

    • Christina Nguyen
    • Ahmed Idowu Omotayo
    • Víctor López Del Amo
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16
  • One method for reducing the impact of vector-borne diseases is through the use of CRISPR-based gene drives, which manipulate insect populations due to their ability to rapidly propagate desired genetic traits into a target population. Here the authors describe a Cas12a gene drive system whose activity can be finetuned in a temperature-dependent manner.

    • Sara Sanz Juste
    • Emily M. Okamoto
    • Víctor López Del Amo
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-8