The authors investigate the in vivo function of microRNA-124a by specifically disrupting Rncr3, the dominant source of miR-124a in mice. Their results suggest that miR-124a is important for maturation and survival of dentate gyrus neurons and retinal cones and acts by repressing Lhx2 translation.
- Rikako Sanuki
- Akishi Onishi
- Takahisa Furukawa