In individuals with inflammation of the central nervous system, B cells enter and accumulate in the cerebrospinal fluid, brain parenchyma and perivascular spaces. Here, Joseph Sabatino and colleagues review the contributions of B cells — both in the periphery and sequestered within the central nervous system — to the pathogenesis of several autoimmune and neurodegenerative diseases.
- Joseph J. Sabatino Jr
- Anne-Katrin Pröbstel
- Scott S. Zamvil
