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Showing 1–2 of 2 results
Advanced filters: Author: Se-Jun Yim Clear advanced filters

  • The trifluoromethyl anion rapidly decomposes into difluorocarbene (:CF2) and fluorine ion, limiting its applicability in synthesis. Here, the authors report a strategy to generate and use the short-lived CF3- intermediate from stable CF3H gas via fast biphasic mixing in precisely customized flow dissolvers.

    • Hyune-Jea Lee
    • Jeong-Un Joo
    • Heejin Kim
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-8

  • Flow reactors have applications in reaction screening and optimisation, but typically operate in linear or radial configurations. Here a bench-top parallel flow synthesiser which distributes reagents between sixteen microreactors allows for rapid optimisation of chemical libraries, with uniform flow distribution even when clogging occurs.

    • Gwang-Noh Ahn
    • Brijesh M. Sharma
    • Dong-Pyo Kim
    ResearchOpen Access
    Communications Chemistry
    Volume: 4, P: 1-8