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Advanced filters: Author: Shahryar Alavi Clear advanced filters

Epilepsy-associated FOXJ3 variants link a transcriptional program of the PTEN-mTOR pathway to neuronal specification and cortical lamination

Researchers identify FOXJ3 variants in focal epilepsy and cortical dysplasia and show that FOXJ3 regulates neuronal migration and cortical layer formation by controlling the PTEN–mTOR pathway; disruption of this process leads to abnormal brain development.

Haw-Yuan Cheng
Chen Liu
Jin-Wu Tsai
ResearchOpen Access09 Mar 2026
Nature Communications

Volume: 17, P: 1-21
Molecular mechanisms of the anti-cancer drug, LY2874455, in overcoming the FGFR4 mutation-based resistance

Fariba Dehghanian
Shahryar Alavi
ResearchOpen Access16 Aug 2021
Scientific Reports

Volume: 11, P: 1-8
Elucidating the genomic basis of rare pediatric neurological diseases in Central Asia and Transcaucasia

Rauan Kaiyrzhanov
Nazira Zharkinbekova
Henry Houlden
Correspondence22 Nov 2024
Nature Genetics

Volume: 56, P: 2582-2584

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