The synthesis of aryl C-glycosides often requires manipulation of protecting groups. Here a general method to prepare aryl C-glycosides from unprotected and stable starting materials has been achieved by photoredox, Ni-catalysed cross-coupling. The protocol was also applied in the synthesis of several sugar–drug conjugates and gliflozin drug molecules.
- Chen Zhang
- Shi-Yang Xu
- Dawen Niu
