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Nature Communications (2)
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Showing 1–8 of 8 results

Advanced filters: Author: Shiyao Xie Clear advanced filters

TRIM21 and OTUD6A orchestrate AKT K27-linked atypical ubiquitination to modulate cancer chemoresistance

The authors here show that the TRIM21–OTUD6A axis controls AKT activity through K27-linked ubiquitination, which is further regulated by S6K1-mediated phosphorylation, introducing a putative therapeutic strategy against AKT-driven cancers.

Qiwei Jiang
Peipei Song
Jianping Guo
Research04 Nov 2025
Nature Structural & Molecular Biology

Volume: 33, P: 84-99
Identifying defect-related quantum emitters in monolayer WSe₂

Jianchen Dang
Sibai Sun
Xiulai Xu
ResearchOpen Access07 Feb 2020
npj 2D Materials and Applications

Volume: 4, P: 1-7
Diabolical points in coupled active cavities with quantum emitters

Jingnan Yang
Chenjiang Qian
Xiulai Xu
ResearchOpen Access13 Jan 2020
Light: Science & Applications

Volume: 9, P: 1-8
S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions

The direct upstream regulation of PDK1 is not fully understood. Here the authors demonstrate that S6K1 directly phosphorylates PDK1 to inhibit AKT kinase activity and its ability to drive tumourigenesis.

Qiwei Jiang
Xiaomei Zhang
Jianping Guo
ResearchOpen Access22 Mar 2022
Nature Communications

Volume: 13, P: 1-14
Magnetoelectric coupling in multiferroics probed by optical second harmonic generation

Here, the authors probe a magneto-electric coupling in freestanding BiFeO₃ by optical second harmonic generation with varying magnetic field and temperature. They find the coupling to be suppressed by strain releasing whereas it remains robust against thermal fluctuations.

Shuai Xu
Jiesu Wang
Guozhen Yang
ResearchOpen Access20 Apr 2023
Nature Communications

Volume: 14, P: 1-8
PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer

Fan Liu
Weixiao Liu
Ping Xie
Research18 Jun 2025
Oncogene

Volume: 44, P: 2997-3013
GINS2 regulates temozolomide chemosensitivity via the EGR1/ECT2 axis in gliomas

Hua He
Lu Liang
Li Cong
ResearchOpen Access11 Mar 2024
Cell Death & Disease

Volume: 15, P: 1-16
Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling

Peng Yu
Ming Liu
Junbo Ge
ResearchOpen Access20 Oct 2020
Cell Death Discovery

Volume: 6, P: 1-11