Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Shuangfeng Zi Clear advanced filters

  • Pulmonary fibrosis involves chronic inflammation and extracellular matrix remodeling but the contribution of neutrophils is unclear. Here the authors show that reverse-migrating neutrophils anchored in the lung extracellular matrix exacerbate fibrosis via ICAM1 and macrophage derived cathepsin C.

    • Liliang Yang
    • Piaopiao Sun
    • Jie Chao
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19

  • While most broadly neutralizing antibodies (bnAb) against Influenza virus target conserved conformational epitopes of the glycoprotein hemagglutinin (HA), Sun et al. characterize a lineage of bnAbs that neutralize group 1 and 2 strains. Structural characterization shows that antibody 28-12 binds a continuous epitope within H3 (group 2) but requires a conformational epitope for H1 (group 1) binding. Comparison of germline-reverted Ab and intermediate mutants provides evidence for an evolutionary adaptation from group 2 to group 1 strain.

    • Xiaoyu Sun
    • Caixuan Liu
    • Bing Sun
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12