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Advanced filters: Author: Shuiying Zhao Clear advanced filters

Maternal factor OTX2 regulates human embryonic genome activation and early development

OTX2 binds to and activates genes involved in embryonic genome activation, including TPRX1 and TPRX2. OTX2 knockdown impairs embryonic genome activation and early development, which can be partially rescued by overexpression of TPRX1 and TPRX2.

Qiuyan Wang
Chuanxin Zhang
Han Zhao
Research27 Oct 2025
Nature Genetics

Volume: 57, P: 2772-2784
Baseline symptom-related white matter tracts predict individualized treatment response to 12-week antipsychotic monotherapies in first-episode schizophrenia

Ying Chen
Shanming Liu
Hengyi Cao
ResearchOpen Access13 Jan 2024
Translational Psychiatry

Volume: 14, P: 1-6
Identification of hub genes associated with diabetic cardiomyopathy using integrated bioinformatics analysis

Hailong Cui
Die Hu
Yanling Liu
ResearchOpen Access03 Jul 2024
Scientific Reports

Volume: 14, P: 1-15