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Advanced filters: Author: Siddharthan B. Thendral Clear advanced filters

  • Thendral et al. describe a mitophagic programme that removes deleterious mtDNA during the oocyte-to-zygote transition in Caenorhabditis elegans, promoting mitochondrial health and offspring survival. Loss of this mitophagy leads to mutant mtDNA accumulation.

    • Siddharthan B. Thendral
    • Sasha Bacot
    • David R. Sherwood
    Research
    Nature Cell Biology
    P: 1-17