Zero- and ultralow-field (ZULF) nuclear magnetic resonance (NMR) has emerged as a complementary technique to conventional high-field (≳1 T) NMR, however, the ability to distinguish heteronuclear coupling remains challenging due to the low abundance of certain nuclei. Here, the authors apply non-hydrogenative parahydrogen-induced hyperpolarization to identify naturally abundant molecules, and demonstrate the detection of pyridine derivatives at a concentration level of ~1 mM.
- Piotr Put
- Seyma Alcicek
- Szymon Pustelny