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Showing 1–2 of 2 results
Advanced filters: Author: Simon Lichtinger Clear advanced filters

  • Amino acid transport is essential for metabolism and cell signalling. Here, authors demonstrate that the gene SLC7A4 encodes a plasma membrane leucine transporter regulated by extracellular pH.

    • Dimitrios Kolokouris
    • Anuja Bothra
    • Simon Newstead
    ResearchOpen Access
    Nature Communications
    P: 1-19

  • The uptake and elimination of beta-lactam antibiotics are facilitated by the proton-coupled peptide transporters. Here authors present cryo-EM structures of PepT2 in complex with the cefadroxil, amoxicillin and cloxacillin to reveal a mechanism of beta-lactam antibiotic recognition

    • Joanne L. Parker
    • Justin C. Deme
    • Simon Newstead
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14