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Showing 1–14 of 14 results

Advanced filters: Author: Simona Genovese Clear advanced filters

Correction: Corrigendum: Passenger deletions generate therapeutic vulnerabilities in cancer

Florian Muller
Simona Colla
Ronald A. DePinho
Amendments and Corrections08 Jul 2015
Nature

Volume: 525, P: 278
Antioxidant capacity and peptidomic analysis of in vitro digested Camelina sativa L. Crantz and Cynara cardunculus co-products

Davide Lanzoni
Francesca Grassi Scalvini
Carlotta Giromini
ResearchOpen Access24 Jun 2024
Scientific Reports

Volume: 14, P: 1-14
Passenger deletions generate therapeutic vulnerabilities in cancer

The ‘collateral’ homozygous deletion of essential redundant housekeeping genes in cancer genomes is shown to confer therapeutic vulnerability on cancer cells with the deletion, without affecting genomically intact normal non-cancerous cells, suggesting new therapeutic opportunities.

Florian L. Muller
Simona Colla
Ronald A. DePinho
Research15 Aug 2012
Nature

Volume: 488, P: 337-342
Growth-related trophic changes of Thunnus thynnus as evidenced by stable nitrogen isotopic values in the first dorsal spine

Paola Rumolo
Angelo Bonanno
Marco Barra
ResearchOpen Access18 Jun 2020
Scientific Reports

Volume: 10, P: 1-10
HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome

Simona di Martino
Carla Azzurra Amoreo
Mario Cioce
Research09 Jan 2018
Oncogene

Volume: 37, P: 1369-1385
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

KRAS mutations are a driver event of pancreatic ductal adenocarcinoma; here, a subpopulation of dormant tumour cells, relying on oxidative phosphorylation for survival, is shown to be responsible for tumour relapse after treatment targeting the KRAS pathway.

Andrea Viale
Piergiorgio Pettazzoni
Giulio F. Draetta
Research10 Aug 2014
Nature

Volume: 514, P: 628-632
Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer

Depletion of Smarcb1 activates the Myc network of signalling cascades, increasing protein metabolism and activation of survival pathways allowing highly aggressive Kras-independent pancreatic cancer cells to develop.

Giannicola Genovese
Alessandro Carugo
Lynda Chin
Research08 Feb 2017
Nature

Volume: 542, P: 362-366
Calreticulin Ins5 and Del52 mutations impair unfolded protein and oxidative stress responses in K562 cells expressing CALR mutants

Simona Salati
Elena Genovese
Rossella Manfredini
ResearchOpen Access22 Jul 2019
Scientific Reports

Volume: 9, P: 1-14
Enamel peptides reveal the sex of the Late Antique ‘Lovers of Modena’

Federico Lugli
Giulia Di Rocco
Stefano Benazzi
ResearchOpen Access11 Sept 2019
Scientific Reports

Volume: 9, P: 1-8
First annulus formation in the European anchovy; a two-stage approach for robust validation

Gualtiero Basilone
Marco Barra
Angelo Bonanno
ResearchOpen Access23 Jan 2020
Scientific Reports

Volume: 10, P: 1-11
Insights on the drivers of genetic divergence in the European anchovy

Gaetano Catanese
Romain Watteaux
Gabriele Procaccini
ResearchOpen Access23 Jun 2017
Scientific Reports

Volume: 7, P: 1-15
Spatio-temporal dynamics of a planktonic system and chlorophyll distribution in a 2D spatial domain: matching model and data

Davide Valenti
Giovanni Denaro
Bernardo Spagnolo
ResearchOpen Access16 Mar 2017
Scientific Reports

Volume: 7, P: 1-13
CALR mutational status identifies different disease subtypes of essential thrombocythemia showing distinct expression profiles

Roberta Zini
Paola Guglielmelli
Rossella Manfredini
ResearchOpen Access08 Dec 2017
Blood Cancer Journal

Volume: 7, P: 1-13
An infant burial from Arma Veirana in northwestern Italy provides insights into funerary practices and female personhood in early Mesolithic Europe

Jamie Hodgkins
Caley M. Orr
Fabio Negrino
ResearchOpen Access14 Dec 2021
Scientific Reports

Volume: 11, P: 1-13