Organelle DNA replication is coupled to nuclear DNA replication in plant cells. In the red alga Cyanidioschyzon merolae, a plastid signalling molecule, Mg-ProtoIX, binds the F-box SCF ubiquitin ligase Fbx3 to inhibit cyclin 1 degradation and thus block nuclear DNA replication.
- Yuki Kobayashi
- Sousuke Imamura
- Kan Tanaka