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Nature Cell Biology (1)

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NOX1 and NPY1R mark regional colon stem cell populations that serve as cancer origins in vivo

Gasnier et al. identify NOX1 and NPY1R as markers of colon stem cells within the mouse caecum and the middle and distal colorectum, respectively. These stem cells contribute to the initiation of invasive colon tumours in mice.

Maxime Gasnier
Tanysha Chi-Ying Chen
Nick Barker
ResearchOpen Access02 Sept 2025
Nature Cell Biology

Volume: 27, P: 1632-1646

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NOX1 and NPY1R mark regional colon stem cell populations that serve as cancer origins in vivo

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