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Showing 1–2 of 2 results
Advanced filters: Author: Stefano Ughetto Clear advanced filters

  • The development of positive supercharged protein loading of cell membrane-based biovesicles, including extracellular vesicles, virus-like particles, and lentiviral vectors, as a strategy to deliver exogenous plasmid DNA to target cells in vitro and in vivo is presented.

    • Koen Breyne
    • Stefano Ughetto
    • Xandra O. Breakefield
    ResearchOpen Access
    Communications Biology
    Volume: 5, P: 1-15

  • Extracellular vesicles transfer a variety of cellular components between cells — including proteins, lipids and nucleic acids. There is now evidence indicating that these cargoes, in particular RNAs, can affect the function of recipient cells. Extracellular vesicles are now being actively tested as biomarkers and delivery vehicles for therapeutic agents.

    • Killian O’Brien
    • Koen Breyne
    • Xandra O. Breakefield
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 21, P: 585-606