Despite the importance of difluoromethyl (CF2H)-bearing centres for pharmaceuticals, there is currently no general strategy for the stereoselective introduction of a CF2H group at chiral centres. Here the authors describe an enantioconvergent difluoromethylation method for racemic alkyl halides to construct such stereocentres.
- Decai Ding
- Lingfeng Yin
- Wei Liu
