Membrane-enclosed reaction compartments are considered important for establishing plausible pathways of prebiotic organization. Here, simple mixing of mononucleotides and cationic peptides in water is shown to produce microdroplets that sequester photo-active molecules, catalytic nanoparticles and enzymes. Such droplets might provide plausible pathways of prebiotic organization prior to the emergence of membrane-based compartmentalization on the early Earth.
- Shogo Koga
- David S. Williams
- Stephen Mann