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Nature Biomedical Engineering (2)
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Showing 1–5 of 5 results

Advanced filters: Author: Steven C. Boggess Clear advanced filters

Network-aware self-supervised learning enables high-content phenotypic screening for genetic modifiers of neuronal activity dynamics

Grosjean et al. present a network-aware, self-supervised learning approach for screening neuronal activity dynamics. They demonstrate its applicability across a range of neural interventions.

Parker Grosjean
Kaivalya Shevade
Martin Kampmann
Research17 Dec 2025
Nature Machine Intelligence

Volume: 7, P: 2009-2025
Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips

The metabolically driven maturation of geometrically aligned human cardiac microtissues on a microfabricated chip reduces cell-phenotype-dependent variabilities in the action-potential morphology and calcium handling of the cardiomyocytes.

Nathaniel Huebsch
Berenice Charrez
Kevin E. Healy
Research27 Apr 2022
Nature Biomedical Engineering

Volume: 6, P: 372-388
Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload

Cardiac tissue engineered to enable the modulation of mechanical resistance to tissue contraction facilitates the modelling of genetic pathologies associated with the absence of a thick-filament accessory protein found in striated heart muscle.

Zhen Ma
Nathaniel Huebsch
Kevin E. Healy
Research10 Sept 2018
Nature Biomedical Engineering

Volume: 2, P: 955-967
CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning

Olivia M. Teter
Amanda McQuade
Martin Kampmann
ResearchOpen Access06 Apr 2025
Molecular Psychiatry

Volume: 30, P: 4176-4193
One-step syntheses of nitrofuranyl benzimidazoles that are active against multidrug-resistant bacteria

Garrett C Moraski
Jane A Thanassi
Marvin J Miller
Research03 Aug 2011
The Journal of Antibiotics

Volume: 64, P: 667-671