Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–9 of 9 results
Advanced filters: Author: Stylianos Bournazos Clear advanced filters

  • Antibodies against dengue virus are linked to increased risk for severe dengue. This study identified the mechanisms by which these antibodies mediate pathogenic activities, guiding the development of novel approaches to control dengue disease.

    • Rachel Yamin
    • Kevin S. Kao
    • Stylianos Bournazos
    Research
    Nature Microbiology
    Volume: 8, P: 1468-1479

  • Optimization of monoclonal antibodies against SARS-CoV-2 for enhanced Fc-effector function increase their effectiveness for prevention and treatment of COVID-19 in multiple animal models of SARS-CoV-2 infection.

    • Rachel Yamin
    • Andrew T. Jones
    • Stylianos Bournazos
    Research
    Nature
    Volume: 599, P: 465-470

  • Authors show that all individuals have asymmetrically glycosylated IgGs—the glycans on each of the Fc protomers are not identical. Asymmetrically monofucosylated IgGs drive dengue disease and are functionally similar to afucosylated IgGs.

    • Tala Azzam
    • Stylianos Bournazos
    • Eric J. Sundberg
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-16

  • Patients with cancer undergoing anti-PD-1 immune checkpoint blockade can experience immune-related adverse effects. Wherry and colleagues examined the immunity elicited upon immunization of patients with cancer and report that anti-PD-1 immunotherapy dynamically affects influenza vaccine-induced immune responses.

    • Ramin Sedaghat Herati
    • David A. Knorr
    • E. John Wherry
    Research
    Nature Immunology
    Volume: 23, P: 1183-1192

  • Antibody-dependent enhancement (ADE) has been described as a mechanism that contributes to the pathogenesis of dengue virus infection. Limited evidence also suggests that it can also occur in other viral infections. Here, the authors explore the history of the ADE phenomenon, discuss the diversity of Fc effector functions and consider its potential relevance in the context of SARS-CoV-2 infection.

    • Stylianos Bournazos
    • Aaron Gupta
    • Jeffrey V. Ravetch
    Reviews
    Nature Reviews Immunology
    Volume: 20, P: 633-643