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Cancer Gene Therapy (3)
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Showing 1–4 of 4 results

Advanced filters: Author: Sui-Chih Tien Clear advanced filters

The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42

Cdc42 activity is important for apical-basal epithelial polarity. Here, the authors show that Shp2 disrupts Cdc42 activation, and by reducing the expression of histone deactylase 6, restores epithelial lumen formation in a cdc42-independent manner.

Sui-Chih Tien
Hsiao-Hui Lee
Zee-Fen Chang
ResearchOpen Access19 Jan 2016
Nature Communications

Volume: 7, P: 1-12
Correction: SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front

Yi-Ing Chen
Sui-Chih Tien
Chun-Mei Hu
Amendments and CorrectionsOpen Access20 Nov 2024
Cancer Gene Therapy

Volume: 32, P: 146
SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front

Yi-Ing Chen
Sui-Chih Tien
Chun-Mei Hu
ResearchOpen Access24 Oct 2024
Cancer Gene Therapy

Volume: 31, P: 1840-1855
RRM1 O-GlcNAcylation inhibition suppresses pancreatic cancer via TK1-mediated replication stress

Sui-Chih Tien
Mei Shih
Chun-Mei Hu
ResearchOpen Access28 Mar 2025
Cancer Gene Therapy

Volume: 32, P: 550-562