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Showing 1–3 of 3 results
Advanced filters: Author: Surinder Kaur Pada Clear advanced filters

  • Plasmid-mediated transmission plays a significant role in the spread of carbapenem-resistant Enterobacterales. Here, analyzing 1,115 carbapenemase-producing plasmids from Singapore, the authors suggest that maintenance of conserved genomes adapted for stable propagation across multiple species, enables evolutionarily successful carbapenemase plasmid genotypes to achieve hyperendemicity in the population.

    • Vanessa Koh
    • Rodrigo Cabrera
    • Oon Tek Ng
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • Carbapenemase-producing Enterobacterales cause healthcare-associated infections but modes of transmission are not well understood. Here, the authors find evidence of transmission without direct patient contact, indicating presence of undetected environmental reservoirs, whilst half of the transmission events are likely due to plasmid-mediated transmission.

    • Kalisvar Marimuthu
    • Indumathi Venkatachalam
    • Oon Tek Ng
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11

  • Comprenhensive analysis of human antibody responses to SARS-CoV-2 variants and animal sarbecoviruses finds that Omicron escapes neutralization more readily than distantly related animal sarbecoviruses.

    • Chee Wah Tan
    • Wan Ni Chia
    • Lin-Fa Wang
    Research
    Nature Microbiology
    Volume: 7, P: 1756-1761