Nature Search

HR3/RORα-mediated cholesterol sensing regulates TOR signaling

Cells respond to cholesterol levels with increased growth. Here, the authors show that HR3/RORα senses cholesterol to regulate TOR signaling, linking cholesterol availability to cell growth, with implications for cholesterol-related diseases and cancer.

Mette Lassen
Keith Pardee
Kim Rewitz
ResearchOpen Access30 Mar 2026
Nature Communications

P: 1-24
Sub-nanometer depth resolution and single dopant visualization achieved by tilt-coupled multislice electron ptychography

The authors implement a computational strategy that couples electron diffraction datasets from a few small-angle projections to more than triple the depth resolution to sub-nanometers and improve dopant detection in bulk crystals.

Zehao Dong
Yang Zhang
Zhen Chen
ResearchOpen Access31 Jan 2025
Nature Communications

Volume: 16, P: 1-10
Maternal high-fat diet exacerbates atherosclerosis development in offspring through epigenetic memory

Li et al. show that maternal exposure to a Western-type diet accelerates atherosclerosis in adult offspring by inducing inflammatory memory in fetal endothelial cells through AP-1-mediated chromatin dynamics. This process, enhanced by 27-hydroxycholesterol, increases chromatin accessibility to inflammatory genes, which can be mitigated by inhibiting AP-1 binding.

Kan Li
Weiqi Qian
Ding Ai
Research14 Mar 2025
Nature Cardiovascular Research

Volume: 4, P: 362-379
Atomically unveiling the structure-activity relationship of biomacromolecule-metal-organic frameworks symbiotic crystal

Biomolecule-metal-organic-frameworks allow for the creation of hybrid materials with desired biological and chemical function. Here, the authors refine the structure-function relationship by identifying the atomic-layer structure of the hybrids and show differences in structure upon different crystallisation pathways.

Linjing Tong
Siming Huang
Gangfeng Ouyang
ResearchOpen Access17 Feb 2022
Nature Communications

Volume: 13, P: 1-9
Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour

The molecular mechanism underlying initial circuit wiring in amygdala is poorly understood. Here the authors show that ephrin-B3 is required for axon targeting and amygdala spinogenesis during a critical period in development, and plays an important role in amygdala mediated fear responses.

Xiao-Na Zhu
Xian-Dong Liu
Nan-Jie Xu
ResearchOpen Access24 Mar 2016
Nature Communications

Volume: 7, P: 1-11
Litchi procyanidins inhibit colon cancer proliferation and metastasis by triggering gut-lung axis immunotherapy

Yuan Yao
Suya Feng
Shuli Man
ResearchOpen Access11 Feb 2023
Cell Death & Disease

Volume: 14, P: 1-11
A tamper-resistant timed secure data transmission protocol based on smart contract

Ke Yuan
Haowen Cao
Chunfu Jia
ResearchOpen Access17 Jul 2023
Scientific Reports

Volume: 13, P: 1-11
Hippocampal Lnx1–NMDAR multiprotein complex mediates initial social memory

Xian-Dong Liu
Peng-Hui Ai
Nan-Jie Xu
ResearchOpen Access26 Nov 2019
Molecular Psychiatry

Volume: 26, P: 3956-3969
Proteasome regulation by reversible tyrosine phosphorylation at the membrane

Lu Chen
Yanan Zhang
Xing Guo
Research18 Feb 2021
Oncogene

Volume: 40, P: 1942-1956
EphB2 mediates social isolation-induced memory forgetting

Xin-Rong Wu
Yu Zhang
Suya Sun
ResearchOpen Access09 Nov 2020
Translational Psychiatry

Volume: 10, P: 1-12

Search

Filter By:

Search

Quick links