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Showing 1–2 of 2 results
Advanced filters: Author: Sven Trienes Clear advanced filters

  • Palladium-catalyzed β-carbon elimination for selective synthesis of diverse heterocyclic skeletons has been a persistent challenge. Here, the authors achieve switchable chemoselective synthesis of C4-carbamoylated indoles and C10-aminophenanthridinones by controlling β-carbon elimination using chlorocarbamates.

    • Bo-Sheng Zhang
    • Yi-Ming Wang
    • Yong-Min Liang
    ResearchOpen Access
    Communications Chemistry
    Volume: 8, P: 1-8

  • Oxylipins are lipid mediators generated during infection for regulating inflammatory responses, but how they are removed is not completely clear. Here the authors show that cellular oxylipin removal is linked to mitochondria β-oxidation by CPT1, a mitochondria lipid importer protein, to serve as a metabolic checkpoint for oxylipin homeostasis and inflammation.

    • Mariya Misheva
    • Konstantinos Kotzamanis
    • Valerie B. O’Donnell
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-20