Nature Search

Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen

Y Kohno
Y Matsuki
Y Sasaguri
ResearchOpen Access14 Feb 2006
British Journal of Cancer

Volume: 94, P: 710-716
Author Correction: High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression

G. Veggiani
R. Villaseñor
S. S. Sidhu
Amendments and CorrectionsOpen Access30 Nov 2022
Nature Communications

Volume: 13, P: 1
A pilot trial of intravital microscopy in the study of the tumor vasculature of patients with peritoneal carcinomatosis

Emmanuel M. Gabriel
Minhyung Kim
Michael B. Wallace
ResearchOpen Access02 Mar 2021
Scientific Reports

Volume: 11, P: 1-13
Steering research on mRNA splicing in cancer towards clinical translation

Although splicing factors are altered in cancer through mutations and copy number variations, their exact role remains challenging to define. In this Roadmap, Anczukow, Thomas-Tikhonenko and colleagues explore recent advances in splicing biology and provide guidance on leveraging these insights to facilitate the clinical application of compounds that target or exploit aberrant splicing patterns in cancer.

Olga Anczukow
Frédéric H.-T. Allain
Andrei Thomas-Tikhonenko
Reviews09 Oct 2024
Nature Reviews Cancer

Volume: 24, P: 887-905
Global metabolic interaction network of the human gut microbiota for context-specific community-scale analysis

The metabolic interactions between gut microbes and host cells play roles in human health. Here, Sunget al. present a literature-curated metabolic network of the human gut microbiota and three human cell types, together with a mathematical approach to identify distinct microbial and metabolic features in gut microbiomes.

Jaeyun Sung
Seunghyeon Kim
Pan-Jun Kim
ResearchOpen Access06 Jun 2017
Nature Communications

Volume: 8, P: 1-12
Ultrastable optical clock with two cold-atom ensembles

Optical clocks with a record low zero-dead-time instability of 6 × 10^–17 at 1 second are demonstrated in two cold-ytterbium systems. The two systems are interrogated by a shared optical local oscillator to nearly eliminate the Dick effect.

M. Schioppo
R. C. Brown
A. D. Ludlow
Research28 Nov 2016
Nature Photonics

Volume: 11, P: 48-52
Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6

The strength of long bones is determined by coalescence of trabeculae during corticalization. Here the authors show that this process is regulated by SOCS3 via a mechanism dependent on IL-6 and expression of sex hormones.

Dae-Chul Cho
Holly J. Brennan
Natalie A. Sims
ResearchOpen Access09 Oct 2017
Nature Communications

Volume: 8, P: 1-13
Prognostic and predictive capacity of tumor infiltrating lymphocytes in the MA.20 regional node radiotherapy trial

N. Riaz
B. E. Chen
T. J. Whelan
ResearchOpen Access29 Aug 2025
npj Breast Cancer

Volume: 11, P: 1-9
Candidalysin is a fungal peptide toxin critical for mucosal infection

This study identifies a cytolytic peptide toxin in the opportunistic human fungal pathogen Candida albicans—the peptide is both a crucial virulence factor that permeabilizes the host cell plasma membrane and a key signal that triggers a host danger response pathway.

David L. Moyes
Duncan Wilson
Julian R. Naglik
Research30 Mar 2016
Nature

Volume: 532, P: 64-68
Directional and reoccurring sequence change in zoonotic RNA virus genomes visualized by time-series word count

Yoshiko Wada
Kennosuke Wada
Toshimichi Ikemura
ResearchOpen Access03 Nov 2016
Scientific Reports

Volume: 6, P: 1-11
Dexamethasone-eluting cochlear implants reduce inflammation and foreign body response in human and murine cochleae

Muhammad Taifur Rahman
Brian J Mostaert
Marlan R. Hansen
ResearchOpen Access20 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
Polarization and entanglement in baryon–antibaryon pair production in electron–positron annihilation

The decay asymmetry and helicity phase of polarized baryon–antibaryon pairs are measured at the BESIII experiment, testing charge–parity symmetry and revealing a discrepancy of the Λ → pπ⁻ decay asymmetry with respect to the current world average.

M. Ablikim
M. N. Achasov
J. H. Zou
Research06 May 2019
Nature Physics

Volume: 15, P: 631-634
SENP3 inhibition suppresses hepatocellular carcinoma progression and improves the efficacy of anti-PD-1 immunotherapy

Peng Wang
Jiannan Qiu
Chunping Jiang
ResearchOpen Access04 Jan 2025
Cell Death & Differentiation

Volume: 32, P: 959-972
ZZ-dependent regulation of p62/SQSTM1 in autophagy

The autophagic receptor p62 recognizes arginylated (Nt-R) substrates through its ZZ domain (p62_ZZ). Here the authors identify a p62 auto regulatory mechanism and provide structural insights into the selective recognition of Nt-R by p62_ZZ and further show that Nt-R binding stimulates p62 oligomerization and macroautophagy.

Yi Zhang
Su Ran Mun
Tatiana G. Kutateladze
ResearchOpen Access22 Oct 2018
Nature Communications

Volume: 9, P: 1-11
Male hormonal contraceptive — are we there yet?

A male hormonal contraceptive would be a welcome addition to current family planning efforts. Herein, we summarize efforts to develop such a contraceptive, with a focus on contraceptive efficacy studies and new compounds that might offer advantages in terms of route of administration and longer half-lives compared with older compounds.

Stephanie T. Page
John K. Amory
Comments & Opinion15 Oct 2018
Nature Reviews Endocrinology

Volume: 14, P: 685-686
Comparative analysis of biological versus chemical synthesis of palladium nanoparticles for catalysis of chromium (VI) reduction

Mpumelelo T. Matsena
Evans M. N. Chirwa
ResearchOpen Access17 Aug 2021
Scientific Reports

Volume: 11, P: 1-15
Application of large language models in medicine

Large language models have received great attention owing to their capabilities to understand and generate human language. This Review aims to provide an overview of the development and deployment of large language models in medicine, including the challenges and opportunities they face.

Fenglin Liu
Hongjian Zhou
David A. Clifton
Reviews07 Apr 2025
Nature Reviews Bioengineering

Volume: 3, P: 445-464
The Law of Storms Developed*

T. B. MAURY
News19 Jun 1873
Nature

Volume: 8, P: 147-148
Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954

Jane A Plumb
Alan Bilsland
W Nicol Keith
Research23 Nov 2001
Oncogene

Volume: 20, P: 7797-7803
Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins

Until now, determining the sequences recognized by an RNA-binding protein has been time and labor intensive. Ray et al. use a custom pool of >210,000 oligos that encode linear and stem-loop RNAs to rapidly determine the sequences bound by nine RNA-binding proteins.

Debashish Ray
Hilal Kazan
Timothy R Hughes
Research28 Jun 2009
Nature Biotechnology

Volume: 27, P: 667-670
BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets

This resource describes a collection of neurons from a variety of light microscopy-based datasets, which can serve as a gold standard for testing automated tracing algorithms, as shown by comparison of the performance of 35 algorithms.

Linus Manubens-Gil
Zhi Zhou
Hanchuan Peng
Research17 Apr 2023
Nature Methods

Volume: 20, P: 824-835
Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region

S Wu
S Huang
X He
Research01 Mar 2010
Oncogene

Volume: 29, P: 2302-2308
Porosity Measurement of Low Permeable Materials Using Gas Expansion Induced Water Intrusion Porosimetry (GEIWIP)

Miad Jarrahi
Douglas W. Ruth
Hartmut M. Holländer
ResearchOpen Access26 Nov 2019
Scientific Reports

Volume: 9, P: 1-13
The X-ray counterpart to the gravitational-wave event GW170817

Detection of X-ray emission at a location coincident with the kilonova transient of the gravitational-wave event GW170817 provides the missing observational link between short gamma-ray bursts and gravitational waves from neutron-star mergers.

E. Troja
L. Piro
Y. Yoon
Research16 Oct 2017
Nature

Volume: 551, P: 71-74
Competition between ADAR and RNAi pathways for an extensive class of RNA targets

ADARs deaminate adenosines to inosines in double-stranded RNA (dsRNA). Interestingly, effects seen when ADARs are knocked out can be suppressed by additional knockout of RNAi machinery, suggesting competition between the two pathways. Genome-wide identification of ADAR targets shows that ADAR edits heavily in regions that generate siRNAs when ADAR is absent, indicating a role for ADAR in regulating dsRNA accumulation and thus siRNA production.

Diane Wu
Ayelet T Lamm
Andrew Z Fire
Research11 Sept 2011
Nature Structural & Molecular Biology

Volume: 18, P: 1094-1101
Gene expression links functional networks across cortex and striatum

The functional connectivity of brain regions can be reflected in a shared molecular architecture. This cross-modal study demonstrates correspondence of spatial patterns of gene expression to limbic and somato/motor cortico-striatal networks in human and non-human primates.

Kevin M. Anderson
Fenna M. Krienen
Avram J. Holmes
ResearchOpen Access12 Apr 2018
Nature Communications

Volume: 9, P: 1-14
Switchable Ultrathin Quarter-wave Plate in Terahertz Using Active Phase-change Metasurface

Dacheng Wang
Lingchao Zhang
Minghui Hong
ResearchOpen Access07 Oct 2015
Scientific Reports

Volume: 5, P: 1-9
Superconductivity in HfTe₅ across weak to strong topological insulator transition induced via pressures

Y. Liu
Y. J. Long
C. Q. Jin
ResearchOpen Access16 Mar 2017
Scientific Reports

Volume: 7, P: 1-7
Prognostic value of serum alkaline phosphatase in spinal metastatic disease

Aditya V. Karhade
Quirina C. B. S. Thio
Joseph H. Schwab
ResearchOpen Access22 Feb 2019
British Journal of Cancer

Volume: 120, P: 640-646
Low-speed fracture instabilities in a brittle crystal

J. R. Kermode
T. Albaret
A. De Vita
Research30 Oct 2008
Nature

Volume: 455, P: 1224-1227
The role of mineral-dust aerosols in polar temperature amplification

Climate models struggle to reproduce the amplitude of polar temperature change observed in palaeoclimatic archives. A synthesis of observational and model data was used to reconstruct atmospheric dust concentrations in the Holocene and Last Glacial Maximum. The impact of aerosols in polar areas is underestimated in simulations for dustier-than-modern conditions; the inclusion of the amplified response to aerosols at high latitudes would improve model predictions.

F. Lambert
J-S. Kug
J-H. Lee
Research06 Jan 2013
Nature Climate Change

Volume: 3, P: 487-491
A novel interstitial deletion of KAL1 in a Japanese family with Kallmann syndrome

K. Nagata
T. Yamamoto
K. Ishitobi
Research01 Jul 2000
Journal of Human Genetics

Volume: 45, P: 237-240
MABP IN THE FIRST 48 HOURS OF LIFE IN PREMATURE INFANTS WITH IVH

M A Adams
L Benson
T G Gardner
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 308
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

Christopher Amos and colleagues perform genome-wide association analysis for lung cancer using cohorts genotyped on the OncoArray and combing these with existing data. They identify 18 loci, 10 of which are new, finding heterogeneity across the different lung cancer subtypes, and explore candidate genes through eQTL analysis in lung tissue.

James D McKay
Rayjean J Hung
Christopher I Amos
Research12 Jun 2017
Nature Genetics

Volume: 49, P: 1126-1132
Observations of a pre-merger shock in colliding clusters of galaxies

A unique merger shock is found in an early phase of two clusters undergoing a major merger, propagating outward along the equatorial plane of the merger. Owing to the rapid approach of the cluster pair, the gas along the merger axis is strongly compressed.

Liyi Gu
Hiroki Akamatsu
Jelle S. Kaastra
Research24 Jun 2019
Nature Astronomy

Volume: 3, P: 838-843
Towards high-energy, high-resolution computed tomography via a laser driven micro-spot gamma-ray source

Y. C. Wu
B. Zhu
Y. Q. Gu
ResearchOpen Access26 Oct 2018
Scientific Reports

Volume: 8, P: 1-7
Magnetic excitations and absence of charge order in the van der Waals ferromagnet Fe_4.75GeTe₂

V. K. Bhartiya
T. Kim
V. Bisogni
ResearchOpen Access21 Jul 2025
npj Quantum Materials

Volume: 10, P: 1-7
Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs

V B Holcomb
H Vogel
P Hasty
Research05 Jun 2006
Oncogene

Volume: 25, P: 7159-7165
A Cenozoic record of the equatorial Pacific carbonate compensation depth

A detailed reconstruction of the calcium carbonate compensation depth—at which calcium carbonate is dissolved—in the equatorial Pacific Ocean over the past 53 million years shows that it tracks ocean cooling, increasing as the ocean cools.

Heiko Pälike
Mitchell W. Lyle
Richard E. Zeebe
Research29 Aug 2012
Nature

Volume: 488, P: 609-614
Author Correction: BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets

Linus Manubens-Gil
Zhi Zhou
Hanchuan Peng
Amendments and Corrections02 Aug 2024
Nature Methods

Volume: 21, P: 1959
The KMT2A recombinome of acute leukemias in 2023

C. Meyer
P. Larghero
R. Marschalek
ResearchOpen Access05 Apr 2023
Leukemia

Volume: 37, P: 988-1005
A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

A high-resolution reference panel based on whole-genome sequencing data enables accurate imputation of HLA alleles across diverse populations and fine-mapping of HLA association signals for HIV-1 host response.

Yang Luo
Masahiro Kanai
Soumya Raychaudhuri
Research05 Oct 2021
Nature Genetics

Volume: 53, P: 1504-1516
(1) 'New Methods of Treatment (2) 'The Surgery of the Diseases of the Appendix Vermiformis and their Complications (3) 'Clinical and Pathological Observations on Acute Abdominal Diseases (4) 'A Short Treatise on Anti-Typhoid Inoculation (5) 'The Suppression of Tuberculosis

R. T. H.
Books & Arts08 Jun 1905
Nature

Volume: 72, P: 122-123
Floral Families

BRIAN T. STYLES
Books & Arts11 Oct 1969
Nature

Volume: 224, P: 195
Agricultural Seeds

MAXWELL T. MASTERS
Editorial09 May 1901
Nature

Volume: 64, P: 30-31
TERT amplification but not activation of canonical Wnt/β-catenin pathway is involved in acral lentiginous melanoma progression to metastasis

Nisha S. Ramani
Phyu P. Aung
Carlos A. Torres-Cabala
Research13 May 2020
Modern Pathology

Volume: 33, P: 2067-2074
Publisher Correction: Landscape of B cell immunity and related immune evasion in human cancers

Xihao Hu
Jian Zhang
X. Shirley Liu
Amendments and Corrections17 May 2019
Nature Genetics

Volume: 51, P: 1068
Imaging nanoparticles in cells by nanomechanical holography

Scanning near-field ultrasonic holography has been used to probe inside cells taken from the lungs of mice that had been exposed to carbon nanohorns, and provides evidence that these particles can enter the cells. The ability to detect nanoparticles below the cell surface could make this technique useful for studying toxicity of nanomaterials.

Laurene Tetard
Ali Passian
Thomas Thundat
Research22 Jun 2008
Nature Nanotechnology

Volume: 3, P: 501-505
Ribozymes in gene therapy

James D. Thompson
Dennis Macejak
Dan T. Stinchcomb
Advertorial01 Mar 1995
Nature Medicine

Volume: 1, P: 277-278
Graham Goddard (1938–1987)

P. O. Andersen
T. V.P Bliss
News & Views25 Mar 1987
Nature

Volume: 326, P: 243

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