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Showing 1–11 of 11 results

Advanced filters: Author: Taesun Min Clear advanced filters

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

Autism is ~4 times more common in males. Jung et al. reveal male-preponderant abnormal behaviors in mice lacking CHD8, a chromatin remodeler, accompanying sexually dimorphic changes in neuronal firing, synaptic transmission, and gene expression.

Hwajin Jung
Haram Park
Eunjoon Kim
Research13 Aug 2018
Nature Neuroscience

Volume: 21, P: 1218-1228
A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels

Epigenetic editing of PCSK9 in the liver, designed to induce DNA methylation and silence gene expression, achieved long-lasting reductions in LDL cholesterol levels in both transgenic mice expressing the human PCSK9 gene and cynomolgus monkeys.

Frederic Tremblay
Qiang Xiong
Aron B. Jaffe
ResearchOpen Access10 Feb 2025
Nature Medicine

Volume: 31, P: 1329-1338
Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice

How NMDAR and GABA neuronal dysfunctions result in impaired social behaviour is unclear. Here, the authors show that NMDARs and gap junctions in cortical PV interneurons modulate burst firing, affecting social behaviour.

Eunee Lee
Seungjoon Lee
Eunjoon Kim
ResearchOpen Access25 Aug 2021
Nature Communications

Volume: 12, P: 1-20
Adnp-mutant mice with cognitive inflexibility, CaMKIIα hyperactivity, and synaptic plasticity deficits

Heejin Cho
Taesun Yoo
Eunjoon Kim
ResearchOpen Access26 Jun 2023
Molecular Psychiatry

Volume: 28, P: 3548-3562
Identification of a subnuclear body involved in sequence-specific cytokine RNA processing

Processing of interleukin RNAs must be tightly controlled during the immune response. Here, the authors identify TDP-43 as a scaffold protein for the formation of a nuclear body that is important for interleukin RNA processing and stability.

Sungwook Lee
Taeyun A. Lee
Boyoun Park
Research05 Jan 2015
Nature Communications

Volume: 6, P: 1-14
Immuno-physiological effects of dietary reishi mushroom powder as a source of beta-glucan on Rohu, Labeo rohita challenged with Aeromonas veronii

Tutul Kumar Saha
Mariom
Zakir Hossain
ResearchOpen Access05 Sept 2023
Scientific Reports

Volume: 13, P: 1-15
Scopolin ameliorates high-fat diet induced hepatic steatosis in mice: potential involvement of SIRT1-mediated signaling cascades in the liver

Ahyoung Yoo
Vikram P. Narayan
Taesun Park
ResearchOpen Access22 May 2017
Scientific Reports

Volume: 7, P: 1-11
Olfactory receptor 10J5 responding to α-cedrene regulates hepatic steatosis via the cAMP–PKA pathway

Tao Tong
Sang Eun Ryu
Taesun Park
ResearchOpen Access25 Aug 2017
Scientific Reports

Volume: 7, P: 1-13
Adenylyl cyclase 3 haploinsufficiency confers susceptibility to diet-induced obesity and insulin resistance in mice

Tao Tong
Ying Shen
Taesun Park
ResearchOpen Access28 Sept 2016
Scientific Reports

Volume: 6, P: 1-12
α-Cedrene protects rodents from high-fat diet-induced adiposity via adenylyl cyclase 3

Tao Tong
Rina Yu
Taesun Park
Research19 Dec 2018
International Journal of Obesity

Volume: 43, P: 202-216
Oleuropein prevents the progression of steatohepatitis to hepatic fibrosis induced by a high-fat diet in mice

Sung Woo Kim
Wonhee Hur
Seung Kew Yoon
ResearchOpen Access25 Apr 2014
Experimental & Molecular Medicine

Volume: 46, P: e92

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Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels

Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice

Adnp-mutant mice with cognitive inflexibility, CaMKIIα hyperactivity, and synaptic plasticity deficits

Identification of a subnuclear body involved in sequence-specific cytokine RNA processing

Immuno-physiological effects of dietary reishi mushroom powder as a source of beta-glucan on Rohu, Labeo rohita challenged with Aeromonas veronii

Scopolin ameliorates high-fat diet induced hepatic steatosis in mice: potential involvement of SIRT1-mediated signaling cascades in the liver

Olfactory receptor 10J5 responding to α-cedrene regulates hepatic steatosis via the cAMP–PKA pathway

Adenylyl cyclase 3 haploinsufficiency confers susceptibility to diet-induced obesity and insulin resistance in mice

α-Cedrene protects rodents from high-fat diet-induced adiposity via adenylyl cyclase 3

Oleuropein prevents the progression of steatohepatitis to hepatic fibrosis induced by a high-fat diet in mice

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