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An NAD⁺ analogue enables assembly of structurally diverse artificial photoenzymes for enantiodivergent [2 + 2] cycloadditions

Expanding the methods for constructing artificial enzymes is of high interest. Now a photoactive cofactor is designed that mimics NAD⁺, allowing its insertion into a range of NAD⁺-binding protein scaffolds to catalyse inter- and intramolecular [2 + 2] cycloaddition reactions.

Ping Du
Jinsi Li
Hui-Jie Pan
Research12 Aug 2025
Nature Catalysis

Volume: 8, P: 822-832
Simvastatin inhibits leptin-induced hypertrophy in cultured neonatal rat cardiomyocytes

Tai-ping Hu
Fang-ping Xu
Jian-dong Luo
Research01 Apr 2006
Acta Pharmacologica Sinica

Volume: 27, P: 419-422
O-Fucosyltransferase SPINDLY attenuates auxin-induced fruit growth by inhibiting ARF6/8-coactivator mediator complex interaction in Arabidopsis

Wang and colleagues uncover the role of SPINDLY-mediated protein O-fucosylation in attenuating auxin-induced fruit growth in Arabidopsis through modulation of activities of AUXIN RESPONSE FACTORs, a co-repressor IAA9 and the coactivator MED complex.

Yan Wang
Seamus Kelley
Tai-ping Sun
ResearchOpen Access28 Apr 2025
Nature Communications

Volume: 16, P: 1-17
Four class A AUXIN RESPONSE FACTORs promote tomato fruit growth despite suppressing fruit set

Mutant combinations of four AUXIN RESPONSE FACTORs in tomato by CRISPR–Cas9 technology reveal their dual function in inhibiting fruit set before pollination while activating fruit growth after fertilization.

Jianhong Hu
Xiao Li
Tai-ping Sun
Research10 Apr 2023
Nature Plants

Volume: 9, P: 706-719
Allogeneic peripheral blood stem cell transplantation in the treatment of leukemia in China

LX Cao
LD Hu
MQ Qin
Correspondence01 Feb 1997
Bone Marrow Transplantation

Volume: 19, P: 403-404
The master growth regulator DELLA binding to histone H2A is essential for DELLA-mediated global transcription regulation

Genetic and ChIP–seq analyses of missense DELLA mutants reveal a role of the DELLA PFYRE subdomain in H2A binding, which stabilizes the transcription factor–DELLA–H2A complexes at the target chromatin for global transcription reprogramming.

Xu Huang
Hao Tian
Tai-Ping Sun
Research03 Aug 2023
Nature Plants

Volume: 9, P: 1291-1305
The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA

Mass spectrometry analysis combined with in vitro assays reveals that SPINDLY is an O-fucosyltransferase that modifies the growth repressor DELLA and consequently enhances its activity to regulate transcription of target genes.

Rodolfo Zentella
Ning Sui
Tai-ping Sun
Research28 Feb 2017
Nature Chemical Biology

Volume: 13, P: 479-485
Assessment of thoracic aorta in different cardiac phases in patients with non-aorta diseases using cardiac CT

Xue Zheng
Yu-jiao Deng
Jing Chen
ResearchOpen Access26 Jul 2021
Scientific Reports

Volume: 11, P: 1-9
3, 4-dihydroxyl-phenyl lactic acid restores NADH dehydrogenase 1 α subunit 10 to ameliorate cardiac reperfusion injury

Xiao-Yuan Yang
Ke He
Jing-Yan Han
ResearchOpen Access01 Jun 2015
Scientific Reports

Volume: 5, P: 1-15
Identification and functional study of a mild allele of SlDELLA gene conferring the potential for improved yield in tomato

Yoshihito Shinozaki
Kentaro Ezura
Tohru Ariizumi
ResearchOpen Access13 Aug 2018
Scientific Reports

Volume: 8, P: 1-15
Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A

Bao-Feng Jin
Kun He
Xue-Min Zhang
Research31 Jul 2003
Oncogene

Volume: 22, P: 4819-4830

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An NAD⁺ analogue enables assembly of structurally diverse artificial photoenzymes for enantiodivergent [2 + 2] cycloadditions

Simvastatin inhibits leptin-induced hypertrophy in cultured neonatal rat cardiomyocytes

O-Fucosyltransferase SPINDLY attenuates auxin-induced fruit growth by inhibiting ARF6/8-coactivator mediator complex interaction in Arabidopsis

Four class A AUXIN RESPONSE FACTORs promote tomato fruit growth despite suppressing fruit set

Allogeneic peripheral blood stem cell transplantation in the treatment of leukemia in China

The master growth regulator DELLA binding to histone H2A is essential for DELLA-mediated global transcription regulation

The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA

Assessment of thoracic aorta in different cardiac phases in patients with non-aorta diseases using cardiac CT

3, 4-dihydroxyl-phenyl lactic acid restores NADH dehydrogenase 1 α subunit 10 to ameliorate cardiac reperfusion injury

Identification and functional study of a mild allele of SlDELLA gene conferring the potential for improved yield in tomato

Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A

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