Dendrimers are attractive polymers with a well-defined structure and multivalent terminal groups. We have designed a novel type of peptidomimetic based on dendrimer by modifying the amino acids at the periphery of the dendrimer. The dendritic peptidomimetic containing Pro and Arg was bound to a model protein, amphiphysin II SH3 domain, at a similar level to a model binding peptide, a Pro-rich sequence of dynamin.
- Chie Kojima
- Harumi Fukada
- Takashi Inui
