G-quadruplexes form from G rich sequences and have previously been suggested to be involved in various aspects of mRNA metabolism. The structure of an RNA quadruplex-duplex junction in complex with an Arg-Gly-rich peptide from Fragile X mental retardation protein (FMRP) now reveals an unprecedented RNA scaffold and principles underlying its specific recognition.
- Anh Tuân Phan
- Vitaly Kuryavyi
- Dinshaw J Patel
