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Showing 1–4 of 4 results
Advanced filters: Author: Terrymar Medina Clear advanced filters

  • Through spatial multiomics, spatial stable isotope tracing and retrospective cohort analyses, this study identifies hyperglycosylation as a driver of Alzheimer’s disease and a promising therapeutic target.

    • Tara R. Hawkinson
    • Zizhen Liu
    • Ramon C. Sun
    ResearchOpen Access
    Nature Metabolism
    P: 1-16

  • This study presents MetaVision3D, a pipeline to integrate mass spectrometry imaging sections into 3D reconstructions of metabolomic maps. The authors also provide a comprehensive 3D metabolome atlas of the brains of healthy mice and two disease models.

    • Xin Ma
    • Cameron J. Shedlock
    • Ramon C. Sun
    Research
    Nature Metabolism
    Volume: 7, P: 842-853

  • Clarke et al. presents a framework for spatial analysis of the metabolome, lipidome, and glycome from a single tissue section using mass spectrometry imaging. Applying this approach, they revealed region-specific metabolic diversity and dysregulation in both normal and diseased mouse brains.

    • Harrison A. Clarke
    • Xin Ma
    • Ramon C. Sun
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13